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RESIDENT’S CORNER
T4 urothelial carcinoma in undiagnosed closed bladder exstrophy in a post-menopausal female
Division of Urology, Department of Surgery, Cook County Health and Hospitals System, Chicago, Illinois, USA
Address correspondence to Dr. Brian J. McArdle, 1900 W.
Polk Street, Suite 465, Chicago, IL 60612 USA
Canadian Journal of Urology 2018, 25(1), 9214-9216.
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It is rare to see an adult presenting with exstrophy of the bladder. Malignant conversion in exstrophy occurs in 4%, with adenocarcinoma as the most common histopathology. We report the first case of metastatic high grade urothelial carcinoma with squamous and sarcomatoid differentiation arising from undiagnosed, closed bladder exstrophy in a female at advanced age with associated bilateral deep vein thrombosis and clot retention. The patient developed clinical progression of disease despite neoadjuvant gemcitabine-cisplatin and salvage (or palliative) radiotherapy. To the best of our knowledge, this is the first reported case of a primary urothelial malignancy in occult bladder exstrophy.Keywords
closed bladder exstrophy, urothelial carcinoma, unreconstructed bladder exstrophy, congenital anomaly
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APA Style
McArdle, B.J., Vidal, P., Psutka, S.P., Hollowell, C.M. (2018). T4 urothelial carcinoma in undiagnosed closed bladder exstrophy in a post-menopausal female. Canadian Journal of Urology, 25(1), 9214–9216.
Vancouver Style
McArdle BJ, Vidal P, Psutka SP, Hollowell CM. T4 urothelial carcinoma in undiagnosed closed bladder exstrophy in a post-menopausal female. Can J Urology. 2018;25(1):9214–9216.
IEEE Style
B.J. McArdle, P. Vidal, S.P. Psutka, and C.M. Hollowell, “T4 urothelial carcinoma in undiagnosed closed bladder exstrophy in a post-menopausal female,” Can. J. Urology, vol. 25, no. 1, pp. 9214–9216, 2018.
Copyright © 2018 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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