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ARTICLE
Cardiovascular Sound Classification Using Neural Architectures and Deep Learning for Advancing Cardiac Wellness
1 Department of CSE, Chandigarh College of Engineering and Technology, Panjab University, Chandigarh, 160019, India
2 Department of ECE, Chandigarh College of Engineering and Technology, Panjab University, Chandigarh, 160019, India
3 Department of Electronic Engineering and Computer Science, Hong Kong Metropolitan University, Hong Kong SAR, 999077, China
4 Center for Interdisciplinary Research, University of Petroleum and Energy Studies (UPES), Dehradun, 248007, India
5 Immersive Virtual Reality Research Group, Department of Computer Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
6 Department of Computer Science and Information Engineering, Asia University, Taichung, 413305, Taiwan
7 Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 40447, Taiwan
8 Symbiosis Centre for Information Technology (SCIT), Symbiosis International University, Pune, 411057, India
9 School of Cybersecurity, Korea University, Seoul, 02841, Republic of Korea
10 Faculty of computing and Information Technology, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
* Corresponding Author: Brij B. Gupta. Email:
(This article belongs to the Special Issue: Exploring the Impact of Artificial Intelligence on Healthcare: Insights into Data Management, Integration, and Ethical Considerations)
Computer Modeling in Engineering & Sciences 2025, 143(3), 3743-3767. https://doi.org/10.32604/cmes.2025.063427
Received 14 January 2025; Accepted 23 May 2025; Issue published 30 June 2025
Abstract
Cardiovascular diseases (CVDs) remain one of the foremost causes of death globally; hence, the need for several must-have, advanced automated diagnostic solutions towards early detection and intervention. Traditional auscultation of cardiovascular sounds is heavily reliant on clinical expertise and subject to high variability. To counter this limitation, this study proposes an AI-driven classification system for cardiovascular sounds whereby deep learning techniques are engaged to automate the detection of an abnormal heartbeat. We employ FastAI vision-learner-based convolutional neural networks (CNNs) that include ResNet, DenseNet, VGG, ConvNeXt, SqueezeNet, and AlexNet to classify heart sound recordings. Instead of raw waveform analysis, the proposed approach transforms preprocessed cardiovascular audio signals into spectrograms, which are suited for capturing temporal and frequency-wise patterns. The models are trained on the PASCAL Cardiovascular Challenge dataset while taking into consideration the recording variations, noise levels, and acoustic distortions. To demonstrate generalization, external validation using Google’s Audio set Heartbeat Sound dataset was performed using a dataset rich in cardiovascular sounds. Comparative analysis revealed that DenseNet-201, ConvNext Large, and ResNet-152 could deliver superior performance to the other architectures, achieving an accuracy of 81.50%, a precision of 85.50%, and an F1-score of 84.50%. In the process, we performed statistical significance testing, such as the Wilcoxon signed-rank test, to validate performance improvements over traditional classification methods. Beyond the technical contributions, the research underscores clinical integration, outlining a pathway in which the proposed system can augment conventional electronic stethoscopes and telemedicine platforms in the AI-assisted diagnostic workflows. We also discuss in detail issues of computational efficiency, model interpretability, and ethical considerations, particularly concerning algorithmic bias stemming from imbalanced datasets and the need for real-time processing in clinical settings. The study describes a scalable, automated system combining deep learning, feature extraction using spectrograms, and external validation that can assist healthcare providers in the early and accurate detection of cardiovascular disease. AI-driven solutions can be viable in improving access, reducing delays in diagnosis, and ultimately even the continued global burden of heart disease.Keywords
Cite This Article
Copyright © 2025 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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