Open Access

ARTICLE

Mindfulness-Based Stress Reduction for Caregiving Stress in Parents of Children with Leukemia

Jinpan Wang^1,#, Yue Yuan^2,#,*

1 Department of Psychology, Northwest Normal University, Lanzhou, 730070, China
2 Department of Education, Yunnan Minzu University, Kunming, 650500, China

* Corresponding Author: Yue Yuan. Email:
# These authors contributed equally to this work

(This article belongs to the Special Issue: Mental Health Promotion and Psychosocial Support in Vulnerable Populations: Challenges, Strategies and Interventions)

International Journal of Mental Health Promotion 2026, 28(1), 12 https://doi.org/10.32604/ijmhp.2025.071212

Received 02 August 2025; Accepted 18 November 2025; Issue published 28 January 2026

Abstract

Background: Childhood leukemia, a malignant proliferative disorder of the hematopoietic system and the most common childhood cancer, poses a significant threat to the lives and health of affected children. For parents, a leukemia diagnosis in their child is a profoundly traumatic event. As primary caregivers, they endure immense psychological distress and caregiving stress throughout the prolonged and demanding treatment process, which can adversely affect their own well-being and caregiving capacity. However, the psychological mechanisms, such as the role of mindfulness, linking caregiver stress to parental coping strategies remain underexplored, and evidence-based interventions to support these parents are needed. Methods: In Study 1, we administered a cross-sectional survey to 242 parents of children with leukemia who were hospitalized at the Affiliated Hospital of Qingdao University between January and August 2024. Participants completed measures assessing caregiver burden, mindful attention awareness, and parental coping style. In Study 2, we further evaluated the effects of a Mindfulness-Based Stress Reduction (MBSR) intervention. Results: The results of Study 1 revealed: (1) The caregiving stress significantly and negatively predicted coping style (β = −1.18, 95% CI [−2.18, −0.18], p < 0.01). (2) Caregiving stress also significantly and negatively predicted mindfulness (β = −1.90, 95% CI [−2.43, −1.38], p < 0.01). (3) Conversely, mindfulness significantly and positively predicted coping style (β = 0.85, 95% CI [0.62, 1.07], p < 0.01). These findings suggest that mindfulness mediates the relationship between caregiver burden and coping style. In Study 2, the experimental group showed a significant decrease in caregiver stress post-intervention (t = 2.24, p < 0.05), a significant increase in mindfulness (t = −4.61, p < 0.001), and a significant improvement in coping style (t = −2.36, p < 0.01). No significant changes were observed in the control group. Conclusion: MBSR can effectively enhance mindfulness and promote adaptive coping strategies, while reducing caregiver burden among parents of children with leukemia.

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