Table of Content

Open AccessOpen Access


Cell bioenergetics: Simple logics, complex solution


Instituto de Histología y Embriología de Mendoza (IHEM, Universidad Nacional de Cuyo, CONICET), Facultad de Ciencias Exactas y Naturales, Mendoza, 5500, Argentina

* Corresponding Author: Luis S. Mayorga,

BIOCELL 2022, 46(10), 2217-2220.


Cells are open systems that exchange energy and molecules with their environment. As any material system, they perform all the complex activities required for homeostasis and reproduction, obeying the thermodynamic laws. This viewpoint will argue that the basic logic governing the energy flux required to preserve cell organization and function is simple: to decrease the activation energy (Ea) of specific processes. Almost none of the possible chemical reactions and energy transformations inside a cell occur at a measurable speed at room or body temperature. Enzymes or other macromolecular structures speed up particular transformations by decreasing the corresponding energetic barriers. However, to maintain the systems in a homeostatic state, capable of sophisticated functions based on this simple strategy requires an inconceivably complex solution. The conclusion will point to the challenging and intricate problems that cells have solved to carve the highly regulated channel through which the energy flows, fueling the work of these nanoscale machines.


Cite This Article

MAYORGA, L. S. (2022). Cell bioenergetics: Simple logics, complex solution. BIOCELL, 46(10), 2217–2220.

This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 1147


  • 580


  • 0


Share Link