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Cannabis and male reproduction: Impact on offspring via sperm epigenome

PAOLA GRIMALDI^*

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, 00133, Italy

* Corresponding Author: PAOLA GRIMALDI. Email:

(This article belongs to the Special Issue: Reproductive Health and Embryonic Development)

BIOCELL 2022, 46(2), 301-304. https://doi.org/10.32604/biocell.2022.017588

Received 22 May 2021; Accepted 04 August 2021; Issue published 20 October 2021

Abstract

Cannabis is the most widely used drug in the Western societies particularly among adolescent and young adults. Epidemiological studies demonstrate that men use cannabis more frequently than women with higher risk in developing cannabis-related disorders. Although the direct adverse effects of cannabis on male reproductive functions have been studied both in humans and animal models, the possible long-term risks for the health of the users and their offspring are still an area of active research.

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