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Reproductive Health and Embryonic Development

Submission Deadline: 31 March 2022 (closed)

Guest Editors


Dr. Zhigang Xue, Tongji University School of Medicine, Shanghai, China. xuezg@tongji.edu.cn


Dr. Jinfeng Xue, Tongji University School of Medicine, Shanghai, China. xuejinfeng@tongji.edu.cn

Summary

Reproductive health is a state of the individual reproductive system, reproductive process and reproductive ability in each stage of life. Disease, pathological changes, gene expression, gene mutation, environment, stress and others can affect reproductive health, and even lead to infertility or sterility, abnormal embryonic development and birth defects. Study on these influencing factors can help to improve people's fertility, reproductive system function as well as the health of offspring, and further to explore the initiation and differentiation of life.

 

This current special issue focuses on a wide range of topics related to reproductive healthy and embryonic development. We invite researchers in this field to submit your original article, reports and reviews in this special issue. Potential topics include but are not limited to the followings:

• Pathogenesis of reproductive and related disease

• Influencing factors of reproductive health and ability

• Assisted reproduction

• Gametogenesis

• Cellular and molecular profiling of early embryonic development

• Fetal developmental abnormalities and prenatal diagnosis


Keywords

Reproductive health, Embryonic development, Pathogenesis, Assisted reproduction, Prenatal diagnosis

Published Papers


  • Open Access

    ARTICLE

    Advanced glycation end-products change placental barrier function and tight junction in rats with gestational diabetes mellitus via the receptor for advanced glycation end products/nuclear factor-κB pathway

    YUEHUA SHI, QIUYING YAN, QIN LI, WEI QIAN, DONGYAN QIAO, DONGDONG SUN, HONG YU
    BIOCELL, Vol.47, No.1, pp. 165-173, 2023, DOI:10.32604/biocell.2022.023043
    (This article belongs to the Special Issue: Reproductive Health and Embryonic Development)
    Abstract The placenta plays an important role in nutrient transport to maintain the growth and development of the embryo. Gestational diabetes mellitus (GDM), the most common complication during pregnancy, highly affects placental function in late gestation. Advanced glycation end-products (AGEs), a complex and heterogeneous group of compounds engaged by the receptor for AGEs (RAGE), are closely associated with diabetes-related complications. In this study, AGEs induced a decrease in the expression of tight junction (TJ) proteins in BeWo cells and increased the paracellular permeability of trophoblast cells by regulating RAGE/NF-κB. Sprague-Dawley (SD) rats injected with 100 mg/kg… More >

  • Open Access

    ARTICLE

    Induction of adaptive response in utero by ionizing radiation: A radiation quality dependent phenomenon

    BING WANG, KAORU TANAKA, KOUICHI MARUYAMA, YASUHARA NINOMIYA, TAKANORI KATSUBE, MITSURU NENOI
    BIOCELL, Vol.46, No.10, pp. 2315-2325, 2022, DOI:10.32604/biocell.2022.021161
    (This article belongs to the Special Issue: Reproductive Health and Embryonic Development)
    Abstract Investigation on possible induction of adaptive response (AR) by high-liner energy transfer (LET) particle radiation for protection against low-LET photon radiation-induced detrimental effects has not yet been performed in utero. This study verified if an AR could be induced by high-LET particle radiation from accelerated heavy ions against low-LET X-ray radiation-induced detrimental effects on fetal mice. Total body irradiation of pregnant C57BL/6J mice were performed by delivering a priming dose ranging from 10 mGy to 320 mGy of particle radiation on gestation day 11 followed one day later by a challenge dose at 3500 mGy from… More >

  • Open Access

    REVIEW

    Current and future therapies for abnormal early embryogenesis with assisted reproductive technology

    XIAOXIA WANG, ZHONGYUAN YAO, DI LIU, CHUNHONG YU, HUI LI
    BIOCELL, Vol.46, No.8, pp. 1803-1806, 2022, DOI:10.32604/biocell.2022.019731
    (This article belongs to the Special Issue: Reproductive Health and Embryonic Development)
    Abstract Each stage of embryonic development, including normal gamete maturation, fertilization, zygotic genome activation, and cleavage, is crucial for human reproduction. Early embryo arrest is a common phenomenon. It is estimated that about 40%–70% of human embryos are arrested at early developmental stages. However, the exact mechanism remains largely uncertain. Embryos can be investigated in vitro by way of the development of in vitro fertilization/intracytoplasmic sperm injection. In addition to iatrogenic factors related to abnormal oocyte/embryo development, multiple gene mutations have been found to be involved in such phenotypes. Based on the knowledge of known etiological factors, several More >

  • Open Access

    ARTICLE

    Should we continue breastfeeding after SARS-CoV-2 infection or mRNA vaccination?

    FEI CHEN, CHUN LUAN, ZICHUN WEI, DECHEN CAI, ZHIWEN CUI, YUYANG LI, HAO WU, XIAOXIA ZHANG, XIAOLI WU
    BIOCELL, Vol.46, No.6, pp. 1425-1433, 2022, DOI:10.32604/biocell.2022.019868
    (This article belongs to the Special Issue: Reproductive Health and Embryonic Development)
    Abstract The coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed a potential threat to infant health. The World Health Organization recommended that the benefits of breastfeeding far outweigh the potential risk of transmission, but there is no denying that the current evidence is insufficient. Moreover, although the COVID-19 mRNA vaccine has played an effective role in protection against infection, individuals have increasing concerns about the safety of breastfeeding after vaccination, and which have caused some breastfeeding women to postpone vaccination or stop breastfeeding early. Thus, in this… More >

  • Open Access

    VIEWPOINT

    Cannabis and male reproduction: Impact on offspring via sperm epigenome

    PAOLA GRIMALDI
    BIOCELL, Vol.46, No.2, pp. 301-304, 2022, DOI:10.32604/biocell.2022.017588
    (This article belongs to the Special Issue: Reproductive Health and Embryonic Development)
    Abstract Cannabis is the most widely used drug in the Western societies particularly among adolescent and young adults. Epidemiological studies demonstrate that men use cannabis more frequently than women with higher risk in developing cannabis-related disorders. Although the direct adverse effects of cannabis on male reproductive functions have been studied both in humans and animal models, the possible long-term risks for the health of the users and their offspring are still an area of active research. More >

  • Open Access

    ARTICLE

    Transcriptome profile analysis of the accompanying migratory parasitic wasp Aenasius bambawalei (= Aenasius arizonensis girault) (Hymenoptera: Encyrtidae): Genes related to fertilization involved at different stage of ovary development

    JUAN ZHANG, JUN HUANG, YAYUAN TANG, XIUZHEN LONG
    BIOCELL, Vol.46, No.1, pp. 195-205, 2022, DOI:10.32604/biocell.2022.016563
    (This article belongs to the Special Issue: Reproductive Health and Embryonic Development)
    Abstract Age-related declines in fertilization success have been reported for a wide range of species. The fertilization of parasitic wasps is closely related to egg production and sperm storage. Aenasius bambawalei (Hymenoptera: Encyridae) is a key parasitic wasp of the important invasive mealybug Phenacoccus solenopsis (Hemiptera: Pseudococcidae). The female offspring ratio of this parasitic wasp was declined with parental age in mass rearing under laboratory conditions. To investigate the molecular mechanisms involved in the reproduction of A. bambawalei, an extensive analysis of the impact of age on transcriptome profile of mated ovaries of this wasp was performed by comparing… More >

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