Open Access
ARTICLE
Arwa Osama NEMER1, Mohammad Saud AL ANAZI2, Ramesa Shafi BHAT1*, Arjumand S. WARSY3, Zeneb A BABAY4, Mohammad H. ADDAR4, Jilani SHAIK2, Sooad AL-DAIHAN1
BIOCELL, Vol.42, No.1, pp. 1-6, 2018, DOI:10.32604/biocell.2018.07005
Abstract Genomic instability and mutations caused by increases in oxidative stress during pregnancy
can damage the fetoplacental unit and can upshot preterm birth. Oxidative damage to DNA may possibly
be involved in etiology of preterm birth (PTB) which can be repaired by DNA repair gene. In the present
study, we assessed the association of base excision repair gene family by analyzing the association of
single nucleotide polymorphisms and genes expression in 8-oxoguanine glycosylase-1 (OGG1) and
apurinic-apyrimidinic endonuclease 1 (APE1) genes with risk of preterm birth in Saudi women. We
analyzed genotypes of four single nucleotide polymorphisms (SNPs) (rs1052133, rs293795, rs2072668 and… More >
Open Access
ARTICLE
Mahmoud MOUSTAFA1,2*, Tarek TAHA3, Mohamed ELNOUBY4, M.A. ABU-SAIED5, Ali SHATI1, Mohamed AL-KAHTANI1, Sulaiman ALRUMMAN1
BIOCELL, Vol.42, No.1, pp. 7-12, 2018, DOI:10.32604/biocell.2018.07002
Abstract Many recent studies are concerned with low cost, easy to handle and alternative renewable energy as a
feasible solution for the upcoming crisis of energy shortage. Microalgae are unicellular entities the can only depend
on CO2, water and solar power to cover their nutritional needs. The current study is concerned with using algal cells
in a polymeric hydrogel, as a cheap source of energy for electricity generation. Chlorella vulgaris has been proved to
be a promising algal species for electricity generation, as compared with Micractinium reisseri. PVA hydrogel has been
used for the immobilization of both algal species in order… More >
Open Access
ARTICLE
Sergio Andrés CARMINATI1,2, María Carolina BARBOSA2, Claudio Marcelo FADER1,2*
BIOCELL, Vol.42, No.1, pp. 13-16, 2018, DOI:10.32604/biocell.2018.07008
Abstract Autophagy is an essential cellular homeostatic mechanism by which intracellular components
are delivered into the lysosomes for degradation and recycling. Autophagy has been related with a
diversity of pathological or physiological dentary processes such as bone remodeling, skeletal aging,
osteoclastogenesis, osteoblastogenesis and different types of oral cancer. Platelet-rich plasma (PRP),
isolated from autologous blood, is a plasma preparation containing a higher concentration of platelets
which contains numerous different growth factors and cytokines that activate several cellular signaling
cascades. The purpose of this study is to investigate the effect of PRP on autophagy stimulation in
both osteoblast precursor 3T3-L1 and non-related… More >
Open Access
ARTICLE
Bingbing ZHANG1, 2, Ying ZHANG1, 2, Xiaomei ZHANG1, 2, Yonggang LV1, 2
BIOCELL, Vol.42, No.1, pp. 17-24, 2018, DOI:10.32604/biocell.2018.06115
Abstract Mechanical microenvironment can strongly affect the metastatic efficiency of circulating
tumor cells. However, the effect of suspension state on their extravasation and the mechanisms involved
are still unclear. To explore the influence of suspension state on extravasation (including adhesion,
spreading and transendothelial migration) of breast tumor cells and its relevant molecular mechanism,
MDA-MB-231 cells were cultured on poly (2-hydroxyethyl methacrylate) coated 6-well plates to minic
the suspension state. Suspension state promoted adhesion, spreading and transendothelial migration
of MDA-MB-231 cells to EAhy926 endothelial cells (ECs) monolayer under both the static condition
and 0.5 dyne/cm2
flow shear stress (FSS). The number of… More >
Open Access
ARTICLE
LINGFENG CHEN1,2,3, ZHIPENG GAO1,2,3, BAIMEI LIU1,2,3, YING LV1,2,3, MEIWEN AN1,2,3,*, JILING FENG4,*
BIOCELL, Vol.42, No.1, pp. 25-34, 2018, DOI:10.32604/biocell.2018.06114
Abstract Arterial characterization of healthy descending thoracic aorta (DTA) is indispensable in determining stress
distributions across wall thickness and different regions that may be responsible for aorta inhomogeneous dilation,
rupture, and dissection when aneurysm occurs. Few studies have shown the inhomogeneity of DTA along the aorta
tree considering changes in circumferential direction. The present study aims to clarify the circumferential regional
characterization of DTA. Porcine DTA tissues were tested according to region and orientation using uniaxial tension.
For axial test, results show that the difference in circumferential direction was mainly in collagen fiber modulus, where
the anterior collagen fiber modulus was… More >