Home / Journals / BIOCELL / Vol.42, No.1, 2018
Table of Content
  • Open Access

    ARTICLE

    Association between preterm birth risk and polymorphism and expression of the DNA repair genes OGG1 and APE1 in Saudi women

    Arwa Osama NEMER1, Mohammad Saud AL ANAZI2, Ramesa Shafi BHAT1*, Arjumand S. WARSY3, Zeneb A BABAY4, Mohammad H. ADDAR4, Jilani SHAIK2, Sooad AL-DAIHAN1
    BIOCELL, Vol.42, No.1, pp. 1-6, 2018, DOI:10.32604/biocell.2018.07005
    Abstract Genomic instability and mutations caused by increases in oxidative stress during pregnancy can damage the fetoplacental unit and can upshot preterm birth. Oxidative damage to DNA may possibly be involved in etiology of preterm birth (PTB) which can be repaired by DNA repair gene. In the present study, we assessed the association of base excision repair gene family by analyzing the association of single nucleotide polymorphisms and genes expression in 8-oxoguanine glycosylase-1 (OGG1) and apurinic-apyrimidinic endonuclease 1 (APE1) genes with risk of preterm birth in Saudi women. We analyzed genotypes of four single nucleotide polymorphisms (SNPs) (rs1052133, rs293795, rs2072668 and… More >

  • Open Access

    ARTICLE

    Feasible design for electricity generation from Chlorella vulgaris using convenient photosynthetic conditions

    Mahmoud MOUSTAFA1,2*, Tarek TAHA3, Mohamed ELNOUBY4, M.A. ABU-SAIED5, Ali SHATI1, Mohamed AL-KAHTANI1, Sulaiman ALRUMMAN1
    BIOCELL, Vol.42, No.1, pp. 7-12, 2018, DOI:10.32604/biocell.2018.07002
    Abstract Many recent studies are concerned with low cost, easy to handle and alternative renewable energy as a feasible solution for the upcoming crisis of energy shortage. Microalgae are unicellular entities the can only depend on CO2, water and solar power to cover their nutritional needs. The current study is concerned with using algal cells in a polymeric hydrogel, as a cheap source of energy for electricity generation. Chlorella vulgaris has been proved to be a promising algal species for electricity generation, as compared with Micractinium reisseri. PVA hydrogel has been used for the immobilization of both algal species in order… More >

  • Open Access

    ARTICLE

    Platelet rich plasma (PRP) induces autophagy in osteoblast precursor 3T3-L1

    Sergio Andrés CARMINATI1,2, María Carolina BARBOSA2, Claudio Marcelo FADER1,2*
    BIOCELL, Vol.42, No.1, pp. 13-16, 2018, DOI:10.32604/biocell.2018.07008
    Abstract Autophagy is an essential cellular homeostatic mechanism by which intracellular components are delivered into the lysosomes for degradation and recycling. Autophagy has been related with a diversity of pathological or physiological dentary processes such as bone remodeling, skeletal aging, osteoclastogenesis, osteoblastogenesis and different types of oral cancer. Platelet-rich plasma (PRP), isolated from autologous blood, is a plasma preparation containing a higher concentration of platelets which contains numerous different growth factors and cytokines that activate several cellular signaling cascades. The purpose of this study is to investigate the effect of PRP on autophagy stimulation in both osteoblast precursor 3T3-L1 and non-related… More >

  • Open Access

    ARTICLE

    Suspension state promotes extravasation of breast tumor cells by increasing integrin β1 expression

    Bingbing ZHANG1, 2, Ying ZHANG1, 2, Xiaomei ZHANG1, 2, Yonggang LV1, 2
    BIOCELL, Vol.42, No.1, pp. 17-24, 2018, DOI:10.32604/biocell.2018.06115
    Abstract Mechanical microenvironment can strongly affect the metastatic efficiency of circulating tumor cells. However, the effect of suspension state on their extravasation and the mechanisms involved are still unclear. To explore the influence of suspension state on extravasation (including adhesion, spreading and transendothelial migration) of breast tumor cells and its relevant molecular mechanism, MDA-MB-231 cells were cultured on poly (2-hydroxyethyl methacrylate) coated 6-well plates to minic the suspension state. Suspension state promoted adhesion, spreading and transendothelial migration of MDA-MB-231 cells to EAhy926 endothelial cells (ECs) monolayer under both the static condition and 0.5 dyne/cm2 flow shear stress (FSS). The number of… More >

  • Open Access

    ARTICLE

    Circumferential variation in mechanical characteristics of porcine descending aorta

    LINGFENG CHEN1,2,3, ZHIPENG GAO1,2,3, BAIMEI LIU1,2,3, YING LV1,2,3, MEIWEN AN1,2,3,*, JILING FENG4,*
    BIOCELL, Vol.42, No.1, pp. 25-34, 2018, DOI:10.32604/biocell.2018.06114
    Abstract Arterial characterization of healthy descending thoracic aorta (DTA) is indispensable in determining stress distributions across wall thickness and different regions that may be responsible for aorta inhomogeneous dilation, rupture, and dissection when aneurysm occurs. Few studies have shown the inhomogeneity of DTA along the aorta tree considering changes in circumferential direction. The present study aims to clarify the circumferential regional characterization of DTA. Porcine DTA tissues were tested according to region and orientation using uniaxial tension. For axial test, results show that the difference in circumferential direction was mainly in collagen fiber modulus, where the anterior collagen fiber modulus was… More >

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