Home / Journals / BIOCELL / Vol.41, No.2-3, 2017
Table of Content
  • Open Access

    ARTICLE

    Kaempferol and docetaxel diminish side population and down-regulate some cancer stem cell markers in breast cancer cell line MCF-7

    SARA SOLTANIAN1, HELIA RIAHIRAD1, ATHAREH PABARJA1, MOHAMMAD REZA KARIMZADEH2, KOLSOUM SAEIDI3,4
    BIOCELL, Vol.41, No.2-3, pp. 33-40, 2017, DOI:10.32604/biocell.2017.41.033
    Abstract Cancer stem cells (CSCs) are a small subpopulation of cancer cells whose resistance to chemotherapy and radiotherapy plays a pivotal role in treatment failure, tumor recurrence and metastasis. Today, the ability of many phytochemicals in targeting of CSCs has been identified. Kaempferol is a plant phytoestrogen that was recognized as a useful agent for targeting cancer cells by apoptosis induction, cell cycle arrest and inhibition of angiogenesis, migration, and invasion of cancer cells. In this study, we compared the effect of docetaxel as a common breast cancer chemotherapy drug and kaempferol on MCF-7 breast CSCs. Results showed that both docetaxel… More >

  • Open Access

    ARTICLE

    Effect of synthesis variables of plasma synthesized polymers on growth of HepG2 cells

    Elizabeth PÉREZ-TEJADA1,4*, Juan MORALES-CORONA3, Luis Ernesto GÓMEZ-QUIRÓZ2, María Concepción GUTIERREZ-RUIZ2, Roberto OLAYO3
    BIOCELL, Vol.41, No.2-3, pp. 41-44, 2017, DOI:10.32604/biocell.2017.41.041
    Abstract Low pressure plasma polymer films were synthesized using pyrrole and allylamine monomers and adding iodine was used (or not) for the reaction in both cases. They were polymerized on glass substrates under the same reaction conditions. Polymerization of allylamine was also studied at different operating powers. These thin polymer films were used as culture surfaces for HepG2 cells, a cell line derived from a human hepatoma. The proliferation, differentiation and two-dimensional propagation until obtaining monolayer of the cells was studied on the different synthetized films and correlations were established between the conditions of synthesis, the physicochemical characteristics obtained and the… More >

  • Open Access

    ARTICLE

    Membrane fluidity regulates high shear stress-induced FAK activation at different subcellular compartments

    FEI XIE1,2, BAOHONG ZHANG1,2, WENFENG XU1, XIAOLING LIAO1,*, QIUHONG HUANG1, BO LIU2,*
    BIOCELL, Vol.41, No.2-3, pp. 45-54, 2017, DOI:10.32604/biocell.2017.41.045
    Abstract Focal adhesion kinase (FAK) plays a vital role in mediating the adaptability of tumor cells under mechanical stimuli. Previous studies revealed that FAK can locate to different cell compartments, and its regulation is highly dependent on its subcellular localization. However, the local FAK activities and its regulation mechanism in different cell compartments of tumor cells in response to fluid shear stress are still unclear. In this study, 5 dyn/cm2 and 20 dyn/cm2 of shear stress was applied to HeLa cells for 30 min. The activities of FAK targeting different subcellular compartments (lipids rafts, non-rafts, focal adhesions and cytoplasm) were investigated… More >

  • Open Access

    ARTICLE

    Freely Available Tool (FAT) for automated quantification of lipid droplets in stained cells

    Diego Masone1,2, Aldana D. Gojanovich1, Yesica R. Frontini-Lopez1, Samanta DEL Veliz1, Marina Uhart1, Diego M. Bustos1,3*
    BIOCELL, Vol.41, No.2-3, pp. 55-58, 2017, DOI:10.32604/biocell.2017.41.055
    Abstract In this study, we propose an automatic procedure for digital image processing. We describe a method that can efficiently quantify and characterize lipid droplets distributions in different cell types in culture. Prospectively, the lipid droplets detection method described in this work could be applied to static or time-lapse data, collected with a simple visible light or fluorescence microscopy equipment. Fully automated algorithms were implemented in Octave, a freely available scientific package. More >

  • Open Access

    ARTICLE

    Evidence for maternal transmission of a putative endosymbiont in the digestive gland of Pomacea canaliculata (Architaenioglossa, Ampullariidae)

    EDUARDO KOCH1,2, ISRAEL A. VEGA1,3,4, ALFREDO CASTRO-VAZQUEZ1,3,4
    BIOCELL, Vol.41, No.2-3, pp. 59-62, 2017, DOI:10.32604/biocell.2017.41.059
    Abstract The digestive gland of the apple snail Pomacea canaliculata lodges two types of pigmented corpuscles (identified as C and K corpuscles) which has been proposed as endosymbiont/s. Both corpuscular types are always present in the digestive gland of adult snails, they are released into the tubuloacinar lumen and are later expelled in the feces. On their part, hatchlings lack any C or K corpuscles in the digestive gland as well as in their feces, whereas C corpuscles appear in both the gland and feces within one week after hatching. Hence, it is possible that the detritivorous hatchlings acquire the putative… More >

  • Open Access

    ARTICLE

    Actin levels fluctuate in the seminiferous epithelium at various stages during spermatogenesis in the rat

    CRISTIAN ACOSTA, MABEL FÓSCOLO, JUAN CARLOS CAVICCHIA*
    BIOCELL, Vol.41, No.2-3, pp. 63-66, 2017, DOI:10.32604/biocell.2017.41.063
    Abstract The testis is a double gland comprised of the sperm-producing seminiferous tubules and a complex endocrine interstice. The former structures generate and release whole cells (exocrine aspect of the gland) while the latter synthesize and release androgens and related hormones. The testis also has poorly understood paracrine connexions. These connexions play an important role during spermatogenesis. A key molecule within these structures is β-actin. Therefore, the present study aims at examining the expression pattern of β-actin during the various stages of the spermatic cycle in the rat. To achieve this goal, we used a combination of trans-illumination assisted microdissection of… More >

  • Open Access

    ARTICLE

    Potential detoxification of aflatoxin B2 using Kluyveromyces lactis and Saccharomyces cerevisiae integrated nanofibers

    MAHMOUD MOUSTAFA1,2*, TAREK TAHA3, MOHAMED ELNOUBY4, NEHAL EL-DEEB5, GAMAL HAMAD6, M.A. ABUSAIED7, SULAIMAN ALRUMMAN1
    BIOCELL, Vol.41, No.2-3, pp. 67-73, 2017, DOI:10.32604/biocell.2017.41.067
    Abstract Current investigation has shown that human exposure to aflatoxins is not limited to the administration of contaminated cereals, but water is another possible source. This study was aimed to design easily applicable method to eliminate aflatoxin B2 (AFB2) from contaminated drinking water. Electrospinning has been used for preparation of probiotic-coated polyvinyl alcohol (PVA) and cellulose acetate (CA) nanofibers. Both of these hybrid nanofibers were studied by scanning electron microscopy (SEM) and Fourier-transformed infrared spectroscopy (FT-IR). SEM showed the proper coating of probiotic strains (Kluyveromyces lactis CBS 2359 and Saccharomyces cerevisiae ATCC 9763) on both nanofiber types. Different areas (1-5 cm2)… More >

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