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Future perspectives on cell therapy for autism spectrum disorder


1 Department of Pediatrics, Yodogawa Christian Hospital, Osaka, 533-0024, Japan
2 Department of Cell Processing and Transfusion, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan

* Corresponding Author: MAKOTO NABETANI. Email: email

BIOCELL 2022, 46(4), 873-879.


Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by impairments in social communication, abnormal to absent verbal communication, the presence of repetitive stereotypic verbal and non-verbal behaviors and restricted interests, with onset early in life. We showed cognitive and behavioral characteristics of ASD by impairment of communication, cognition, perception, motor skills, executive function, theory of mind and emotion control. Recently, pathogenesis of immune pathology in the brains of individuals with ASD has been focused. New therapeutic approaches in the viewpoints of immune modulation and microglial function are logical for novel treatments for individuals with ASD. Cell therapies such as umbilical cord blood cells and mesenchymal stromal cells for ASD will be a challenging and encouraging field in the future clinical study with progress of biotechnological science.


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APA Style
NABETANI, M., MUKAI, T. (2022). Future perspectives on cell therapy for autism spectrum disorder. BIOCELL, 46(4), 873-879.
Vancouver Style
NABETANI M, MUKAI T. Future perspectives on cell therapy for autism spectrum disorder. BIOCELL . 2022;46(4):873-879
IEEE Style
M. NABETANI and T. MUKAI, "Future perspectives on cell therapy for autism spectrum disorder," BIOCELL , vol. 46, no. 4, pp. 873-879. 2022.

cc This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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