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Phototoxic compounds and biological activity of extracts from Eupatorium morifolium Mill. (Asteraceae)

Pérez-Amador1 MC, V Muñoz Ocotero1, F García Jiménez2
Facultad de Ciencias, Departamento de Biología.
Instituto de Química. Universidad Nacional Autónoma de México. Ciudad Universitaria. 04510. México, D.F. México.
* Corresponding Authors:Address Correspondence to: Dr. Maria Cristina Pérez-Amador; Facultad de Ciencias. UNAM. Circuito Exterior s/n Ciudad Universitaria. C.P. 04510. México D.F.; e-mail: ,

Phyton-International Journal of Experimental Botany 2008, 77(all), 21-29. https://doi.org/10.32604/phyton.2008.77.021

Abstract

Leaves of Eupatorium morifolium Mill. were analyzed for phototoxic compounds, and the toxicity of their hexane extract was evaluated against Bacillus subtilis. The phototoxic compounds were analyzed by TLC. In the plate, pale blue spots indicated the presence of these compounds. This was confirmed by the UV extract spectrum and the antibacterial activity against Bacillus subtilis. The biological activity of the leaf extracts (hexane, ethyl acetate or methanol) was also studied. The antiinflammatory activity was determined using the edema test on mouse ears, and the bactericide activity was assayed against Bacillus subtilis and Escherichia coli. A strong anti-inflammatory activity was shown by the leaf extracts. The ethyl acetate extract exhibited the strongest bactericide activity, followed by the methanol and hexane extracts.

Keywords

Asteraceae, phototoxic compounds, bactericide activity, 12-O-tetradecanoylphorbol-13-acetate (TPA)

Cite This Article

, P., Jiménez, F. G. (2008). Phototoxic compounds and biological activity of extracts from Eupatorium morifolium Mill. (Asteraceae). Phyton-International Journal of Experimental Botany, 77(all), 21–29.



This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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