Shengda Chen^1,2, Candra Ratna Sari¹, Patrick Segers², Guixue Wang¹, Xingshuang Ma^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 69-70, 2019, DOI:10.32604/mcb.2019.05740

Abstract This article has no abstract. More >

Ju Huang¹, Cuiru Sun^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 67-68, 2019, DOI:10.32604/mcb.2019.05738

Abstract Intravascular optical coherence tomography (OCT) has the characteristics of high resolution and fast imaging speed. Continuous images of the same section of the same vessel can reflect the deformation characteristics of the vessel wall under different blood pressure. Digital image processing may be used to segment various structures on the vascular wall and extract the deformation incorporating with biomechanical analysis. Image filtering plays a very important role in image processing. Median filter was used to filter salt and pepper noise in OCT images. Fuzzy function gray processing method was used to suppress irrelevant information and More >

Xiang Shen^1,*, Hongfei Zhu¹, Song Ji¹, Jiabao Jiang¹, Yongquan Deng¹

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 65-65, 2019, DOI:10.32604/mcb.2019.05737

Abstract In order to open up the blocked lumen and remodel the blood environment, vascular stents were usually used to transplant into narrowed blood vessels. Due to its minimally invasive and highly efficiency, stenting has achieved great success in the treatment of cardiovascular diseases. However, failure of stents due to its fatigue will damage the arterial wall, leading to adverse reactions such as thrombosis and in-stent restenosis (ISR), which severely limited its long-term outcome. Therefore, it was very important to predict the service life of stents, especially in tapered arteries.
FEA was adopted to study the… More >

Junjie Jia¹, Cuiru Sun^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 61-64, 2019, DOI:10.32604/mcb.2019.05736

Abstract Intravascular optical coherence tomography (IVOCT) has been employed to clinical coronary imaging for several years. But the influence of flushing and OCT catheter to the blood vessel biomechanical properties have not been studied. In this paper, IVOCT imaging is integrated with the fluid-structure interaction (FSI) simulation to study the blood flow velocity and the stress distribution of a porcine carotid artery during IVOCT imaging. 3D geometric model is built based on the in vivo OCT images, and a hyperelastic model is employed for the material properties of the vascular wall. The blood flow profile and wall More >

Guangyu Zhu¹, Wei Cai^2,*, Qi Yuan¹, Lianglong Chen²

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 59-60, 2019, DOI:10.32604/mcb.2019.05733

Abstract This article has no abstract. More >

Yifan Yin¹, Chunliu He¹, Biao Xu², Zhiyong Li^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 57-57, 2019, DOI:10.32604/mcb.2019.05732

Abstract The tissue composition and morphological structure of atherosclerotic plaques determine its stability or vulnerability. Intravascular optical coherence tomography (IVOCT) has rapidly become the method of choice for assessing the pathology of the coronary arterial wall in vivo due to its superior resolution. However, in clinical practice, the analysis of plaque composition of OCT images mainly relies on the interpretation of images by well-trained experts, which is a time-consuming, labor-intensive procedure and it is also subjective. The purpose of this study is to use the Convolutional neural network (CNN) method to automatically extract the best feature… More >

Guangyu Zhu¹, Yuan Wei¹, Qi Yuan^1,*, Ge Yan², Jian Yang²

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 55-56, 2019, DOI:10.32604/mcb.2019.05730

Abstract This article has no abstract. More >

Kun Peng¹, Xinyang Cui¹, Aike Qiao^1,*, Makoto Ohta², Koji Shimoyama², Yongliang Mu³

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 53-53, 2019, DOI:10.32604/mcb.2019.05729

Abstract Biodegradable stents which can avoid risks caused by incompatibility between artery and permanent stents are attracting much interests. However, biodegradable stents have not been extensively applied in clinical therapy because of their insufficient scaffold performance as a result of poor Young’s Modulus of biodegradable materials and weaken structures in degradation process. In this study, a patented stent and a common stent were simulated to degrade in a 40% stenotic vesel based on a corrosion model involving uniform corrosion and stress corrosion. In the degradation process, the scaffold performance of the two stents and their functionality… More >

Chunbo Jin¹, Youjun Liu^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 51-52, 2019, DOI:10.32604/mcb.2019.05728

Abstract Coronary heart disease (CHD) is one of the most common forms of heart disease, which means that coronary stenosis can cause insufficient blood supply to the heart and lead to coronary heart disease. Coronary artery bypass grafting (coronary bypass) is often used in the treatment of patients with coronary heart disease. After surgery, because the stenosis of the coronary artery is not completely occluded, the blood flow through it will compete with the blood flow of the graft, making it possible to transplant blood vessels. The blood flow is affected, reducing long-term permeability. When the… More >

Muyi Guo¹, Yan Cai¹, Zhiyong Li^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 49-49, 2019, DOI:10.32604/mcb.2019.05727

Abstract Observational studies have identified angiogenesis from the adventitial vasa vasorum and intraplaque hemorrhage (IPH) as critical factors in atherosclerotic plaque progression and destabilization. Here we propose a mathematical model incorporating intraplaque neovascularization and hemodynamic calculation for the quantitative evaluation of atherosclerotic plaque hemorrhage. An angiogenic microvasculature based on histology of a patient’s carotid plaque is generated by two-dimensional nine-point model of endothelial cell migration. Three key cells (endothelial cells, smooth muscle cells and macrophages) and three key chemicals (vascular endothelial growth factors, extracellular matrix and matrix metalloproteinase) are involved in the intraplaque angiogenesis model, and… More >