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  • Open Access

    EDITORIAL

    Ten Years of Progress in Advanced Prostate Cancer at the AUA

    Leonard G. Gomella

    Canadian Journal of Urology, Vol.33, No.2, pp. 233-234, 2026, DOI:10.32604/cju.2026.083134 - 20 April 2026

    Abstract This article has no abstract. More >

  • Open Access

    LEGENDS IN UROLOGY

    Legends in Urology

    Martin A. Koyle

    Canadian Journal of Urology, Vol.33, No.2, pp. 235-238, 2026, DOI:10.32604/cju.2026.081440 - 20 April 2026

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    Can AI and predictive models accurately predict stone-free status? a systematic review and meta-analysis

    Yahya Ghazwani1,2,3, Mohammad Alghafees1,2,3,*, Mishari Alshasha1,2,3, Fahad Brayan1,2,3, Abdulrahman Alsayyari1,2,3, Ali Alyami1,2,3

    Canadian Journal of Urology, Vol.33, No.2, pp. 291-308, 2026, DOI:10.32604/cju.2026.077411 - 20 April 2026

    Abstract Objectives: The emergence of artificial intelligence (AI) and predictive modeling offers prospects for clinical, anatomical, and imaging factor combination, like radiomics, to help with stone-free status (SFS) estimation and peroperative decision-making. The goal of this study was, therefore, to define the present performance range, determine sources of heterogeneity, and determine methodological practices permitting reliable implementation by varied circumstances. Methods: We searched six bibliographic databases through 19 September 2025. Studies deriving or validating AI/predictive models for SFS after ureteroscopy were eligible. Independent dual screening, duplicate data extraction, and risk-of-bias consideration using QUADAS-AI were conducted. Results: Five retrospective… More >

  • Open Access

    ARTICLE

    Proximal/Distal ureteral diameter ratio as a predictor of spontaneous passage in <10 mm ureteral stones

    İbrahim Üntan1,*, Nuh Aldemir2

    Canadian Journal of Urology, Vol.33, No.2, pp. 239-248, 2026, DOI:10.32604/cju.2026.076805 - 20 April 2026

    Abstract Background: Ureteral stones are a common cause of acute renal colic, and while most small stones pass spontaneously, reliable predictors of passage are needed to optimize patient selection for conservative management. This study aims to evaluate the role of radiologic, clinical and laboratory parameters—particularly the proximal/distal (P/D) ureteral diameter ratio—in predicting spontaneous passage of <10 mm ureteral stones. Materials and Methods: This retrospective cohort study included 277 patients diagnosed with ureteral calculi <10 mm on non-contrast computed tomography between September 2022 and September 2025. Pregnant patients, solitary kidney cases, congenital anomalies, active urinary infection, and incomplete… More > Graphic Abstract

    Proximal/Distal ureteral diameter ratio as a predictor of spontaneous passage in <10 mm ureteral stones

  • Open Access

    ARTICLE

    Analysis of risk factors for MRI-invisible prostate cancer—the significance of AGGF1 immunohistochemical detection and PSAD

    Jingcheng Lyu1,2,#, Ruiyu Yue1,2,#, Ye Tian1,2,*, Boyu Yang1,2,*

    Canadian Journal of Urology, Vol.33, No.2, pp. 361-375, 2026, DOI:10.32604/cju.2026.074814 - 20 April 2026

    Abstract Objectives: Patients with a multi-parameter magnetic resonance imaging (mpMRI) prostate imaging report and data system (PI-RADS) score ≤ 3, but with clinically significant prostate cancer (CSPCa) detected by biopsy, are termed MRI-Invisible prostate cancer (MRI(-)PCa). This study aims to explore risk factors for MRI(-)PCa and identify immunohistochemical indicators with predictive significance. Methods: A retrospective analysis was conducted on 376 patients with PI-RADS score ≤ 3 who underwent 24-needle systematic prostate biopsy at Beijing Friendship Hospital, Capital Medical University (January 2015 to October 2025). Clinical data, imaging data, and Angiogenic factor with G and FHA domain… More >

  • Open Access

    ARTICLE

    Evaluating pain management strategies following hypospadias repair: a survey of pediatric urologists

    Jaisa Kaufmann1,*, Max Bouvette2, Abdul Qadar1, Dominic Frimberger1, Adam Rensing1, Bhalaajee Meenakshi-Sundaram1

    Canadian Journal of Urology, Vol.33, No.2, pp. 451-457, 2026, DOI:10.32604/cju.2026.074190 - 20 April 2026

    Abstract Background: Pediatric opioid use has been associated with serious adverse effects, including persistent use and overdose. Recent studies have shown that opioid needs may be minimal following outpatient pediatric urologic surgery. Post-operative pain regimens following pediatric penile surgery are not standardized. This study aimed to identify current opioid prescribing practices following hypospadias repair. Methods: An online survey was administered to members of the Societies for Pediatric Urology, including eight questions surrounding physician demographics, hypospadias repair case volume, attitudes regarding opioid prescription in pediatric urology, and post-operative pain regimens. Responses were stratified for analysis. Results: A total… More >

  • Open Access

    CASE REPORT

    Robot-assisted partial nephrectomy during simultaneous extracorporeal membrane oxygenation and impella® in a candidate for left ventricular assist device as a bridge for cardiac transplant: a case report

    Francesco Cianflone1, Giuseppe Ottone Cirulli1, Alessio Villano1, Mohammad Eisa Ali1, Mirko Belliato2, Roberto Veronesi2, Germana Bichisao3, Carlo Marchetti1, Simona Secondino4, Paolo Pedrazzoli4,5, Stefano Pelenghi6, Carlo Pellegrini6,7, Andrea Ringressi1, Richard Naspro1,7,*

    Canadian Journal of Urology, Vol.33, No.2, pp. 459-470, 2026, DOI:10.32604/cju.2025.073002 - 20 April 2026

    Abstract Background: Robot-assisted partial nephrectomy (RAPN) is standard for cT1 renal masses, but its feasibility in patients on temporary mechanical circulatory support is poorly documented. We report RAPN performed while a patient was simultaneously supported with venous-arterial extracorporeal membrane oxygenation (VA ECMO) and Impella®, as part of a staged plan for left ventricular assist device (LVAD) implantation and eventual heart transplantation. Case Presentation: A 51-year-old man presented with ST-elevation myocardial infarction complicated by cardiogenic shock requiring percutaneous coronary intervention with stenting, dual antiplatelet therapy, and combined VA ECMO–Impella® support. During workup for cardiac transplant, computed tomography (CT) staging… More >

  • Open Access

    ARTICLE

    Bladder cancer patients hospitalized in a medicine ward including three fuo cases following bacillus calmette-guérin immunotherapy

    George Liatsos*, Kalliopi Zioutou, Konstantinos Avramidis, Konstantinos Vamvakaris, Maria Potamiti-Komi, Dimitrios Vassilopoulos

    Canadian Journal of Urology, Vol.33, No.2, pp. 349-360, 2026, DOI:10.32604/cju.2026.072711 - 20 April 2026

    Abstract Objectives: Bladder cancer (BC) is a prevalent malignancy with evolving treatment strategies and an increasingly aging patient population, resulting in a growing and complex burden of hospitalizations that extends beyond urological care and remains insufficiently characterized in real-world Internal Medicine settings. This study aimed to analyze the clinical data and outcomes for patients with BC admitted to the medicine ward. Additionally, this research presents three cases of fever of unknown origin, which all exhibited identical clinical and laboratory findings but ultimately resulted in different disease diagnoses. Methods: This retrospective case-series study included all adult patients… More >

  • Open Access

    ARTICLE

    Urodynamic de-obstruction and symptom improvement after thulium laser vaporization (ThuVAP): evidence from a prospective paired study

    Simone Tammaro1, Francesco Di Fiore2, Felice Crocetto3, Celeste Manfredi1,*, Claudia Collà Ruvolo3, Gianluigi Califano3, Biagio Barone4, Davide Arcaniolo1, Lorenzo Spirito1, Francesco Paolo Calace2, Pasquale Reccia2, Ferdinando Fusco1, Marco De Sio1, Raffaele Balsamo2

    Canadian Journal of Urology, Vol.33, No.2, pp. 249-259, 2026, DOI:10.32604/cju.2025.072617 - 20 April 2026

    Abstract Background: Thulium laser vaporization of the prostate (ThuVAP) is an established treatment for benign prostatic obstruction, but its impact on urodynamic parameters remains poorly defined. This study aimed to quantify the de-obstructive efficacy of ThuVAP through pre- and postoperative urodynamic comparisons and to assess the relationship between urodynamic improvement and symptom relief. Methods: In a prospective single-center cohort (June 2022–June 2024), men with urodynamically confirmed obstruction underwent standardized ThuVAP with a 200-W thulium:YAG system. Baseline and 6-month invasive urodynamics and 12-month clinical follow-up were performed. The primary endpoint was the change in the bladder outlet… More >

  • Open Access

    ARTICLE

    Genetic evidence against a causal relationship between myocardial infarction and urological malignancies

    Wei Zhang, Xixi Peng*

    Canadian Journal of Urology, Vol.33, No.2, pp. 387-401, 2026, DOI:10.32604/cju.2026.072565 - 20 April 2026

    Abstract Background: Observational studies have suggested potential associations between myocardial infarction (MI) and cancer risk, but the causal nature of these relationships remains unclear due to confounding factors and reverse causation. We aimed to investigate the bidirectional causal relationships between MI and urinary system cancers using genetic instruments. Methods: We conducted a two-sample Mendelian randomization (MR) analysis using summary statistics from large-scale genome-wide association studies. Genetic variants associated with MI were used as instrumental variables (n = 19 SNPs for prostate cancer [PCa] and malignant neoplasm of kidney [MRN], n = 6 SNPs for bladder cancer,… More >

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