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  • Open Access

    ARTICLE

    Enhancing Deep Learning Semantics: The Diffusion Sampling and Label-Driven Co-Attention Approach

    Chunhua Wang1,2, Wenqian Shang1,2,*, Tong Yi3,*, Haibin Zhu4

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 1939-1956, 2024, DOI:10.32604/cmc.2024.048135

    Abstract The advent of self-attention mechanisms within Transformer models has significantly propelled the advancement of deep learning algorithms, yielding outstanding achievements across diverse domains. Nonetheless, self-attention mechanisms falter when applied to datasets with intricate semantic content and extensive dependency structures. In response, this paper introduces a Diffusion Sampling and Label-Driven Co-attention Neural Network (DSLD), which adopts a diffusion sampling method to capture more comprehensive semantic information of the data. Additionally, the model leverages the joint correlation information of labels and data to introduce the computation of text representation, correcting semantic representation biases in the data, and More >

  • Open Access

    ARTICLE

    LA-D-B1, a novel Abemaciclib derivative, exerts anti-breast cancer effects through CDK4/6

    LING MA1,#, ZIRUI JIANG1,#, XIAO HOU1, YUTING XU1, ZIYUN CHEN1, SIYI ZHANG1, HANXUE LI1, SHAOJIE MA1, GENG ZHANG2, XIUJUN WANG1,*, JING JI1,*

    BIOCELL, Vol.48, No.5, pp. 847-860, 2024, DOI:10.32604/biocell.2024.050868

    Abstract Background: Regulatory proteins involved in human cellular division and proliferation, cyclin-dependent kinases 4 and 6 (CDK4/6) are overexpressed in numerous cancers, including triple-negative breast cancer (TNBC). TNBC is a common pathological subtype of breast cancer that is prone to recurrence and metastasis, and has a single treatment method. As one of the CDK4/6 inhibitors, abemaciclib can effectively inhibit the growth of breast tumors. In this study, we synthesized LA-D-B1, a derivative of Abemaciclib, and investigated its anti-tumor effects in breast cancer. Methods: Cellular viability was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Cell cloning and… More >

  • Open Access

    ARTICLE

    Complementary-Label Adversarial Domain Adaptation Fault Diagnosis Network under Time-Varying Rotational Speed and Weakly-Supervised Conditions

    Siyuan Liu1,*, Jinying Huang2, Jiancheng Ma1, Licheng Jing2, Yuxuan Wang2

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 761-777, 2024, DOI:10.32604/cmc.2024.049484

    Abstract Recent research in cross-domain intelligence fault diagnosis of machinery still has some problems, such as relatively ideal speed conditions and sample conditions. In engineering practice, the rotational speed of the machine is often transient and time-varying, which makes the sample annotation increasingly expensive. Meanwhile, the number of samples collected from different health states is often unbalanced. To deal with the above challenges, a complementary-label (CL) adversarial domain adaptation fault diagnosis network (CLADAN) is proposed under time-varying rotational speed and weakly-supervised conditions. In the weakly supervised learning condition, machine prior information is used for sample annotation More >

  • Open Access

    ARTICLE

    Aggravation of Cancer, Heart Diseases and Diabetes Subsequent to COVID-19 Lockdown via Mathematical Modeling

    Fatma Nese Efil1, Sania Qureshi1,2,3, Nezihal Gokbulut1,4, Kamyar Hosseini1,3, Evren Hincal1,4,*, Amanullah Soomro2

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 485-512, 2024, DOI:10.32604/cmes.2024.047907

    Abstract The global population has been and will continue to be severely impacted by the COVID-19 epidemic. The primary objective of this research is to demonstrate the future impact of COVID-19 on those who suffer from other fatal conditions such as cancer, heart disease, and diabetes. Here, using ordinary differential equations (ODEs), two mathematical models are developed to explain the association between COVID-19 and cancer and between COVID-19 and diabetes and heart disease. After that, we highlight the stability assessments that can be applied to these models. Sensitivity analysis is used to examine how changes in… More >

  • Open Access

    ARTICLE

    Scheme Based on Multi-Level Patch Attention and Lesion Localization for Diabetic Retinopathy Grading

    Zhuoqun Xia1, Hangyu Hu1, Wenjing Li2,3, Qisheng Jiang1, Lan Pu1, Yicong Shu1, Arun Kumar Sangaiah4,5,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 409-430, 2024, DOI:10.32604/cmes.2024.030052

    Abstract Early screening of diabetes retinopathy (DR) plays an important role in preventing irreversible blindness. Existing research has failed to fully explore effective DR lesion information in fundus maps. Besides, traditional attention schemes have not considered the impact of lesion type differences on grading, resulting in unreasonable extraction of important lesion features. Therefore, this paper proposes a DR diagnosis scheme that integrates a multi-level patch attention generator (MPAG) and a lesion localization module (LLM). Firstly, MPAG is used to predict patches of different sizes and generate a weighted attention map based on the prediction score and… More >

  • Open Access

    ARTICLE

    Matrix Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF)-Mass Spectrometry and 13C-NMR-Identified New Compounds in Paraberlinia bifoliolata (Ekop-Beli) Bark Tannins

    Liliane Nga1, Benoit Ndiwe1,2, Achille Bernard Biwolé1, Antonio Pizzi3,*, Jean Jalin Eyinga Biwole1, Joseph Zobo Mfomo1

    Journal of Renewable Materials, Vol.12, No.3, pp. 553-568, 2024, DOI:10.32604/jrm.2023.046568

    Abstract Extracts of plant origin, particularly tannins, are attracting growing interest for the sustainable development of materials in the industrial sector. The discovery of new tannins is therefore necessary. The aim of this work was to contribute to the understanding of the properties of Paraberlinia bifoliolata tannin by Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectroscopy MALDI-TOF/MS and Carbon 13 Nuclear Magnetic Resonance (13C NMR). The chemical composition of tannin extracted from Paraberlinia bifoliolata bark was determined, as was the mechanical strength of the resin hardened with Acacia nilotica extracts. Yield by successive water extraction was 35%. MALDI-TOF/MS… More >

  • Open Access

    ARTICLE

    Causality-Driven Common and Label-Specific Features Learning

    Yuting Xu1,*, Deqing Zhang1, Huaibei Guo2, Mengyue Wang1

    Journal on Artificial Intelligence, Vol.6, pp. 53-69, 2024, DOI:10.32604/jai.2024.049083

    Abstract In multi-label learning, the label-specific features learning framework can effectively solve the dimensional catastrophe problem brought by high-dimensional data. The classification performance and robustness of the model are effectively improved. Most existing label-specific features learning utilizes the cosine similarity method to measure label correlation. It is well known that the correlation between labels is asymmetric. However, existing label-specific features learning only considers the private features of labels in classification and does not take into account the common features of labels. Based on this, this paper proposes a Causality-driven Common and Label-specific Features Learning, named CCSF More >

  • Open Access

    ARTICLE

    Association of Congenital Heart Defects (CHD) with Factors Related to Maternal Health and Pregnancy in Newborns in Puerto Rico

    Yamixa Delgado1,*, Caliani Gaytan1, Naydi Perez2, Eric Miranda3, Bryan Colón Morales1, Mónica Santos1

    Congenital Heart Disease, Vol.19, No.1, pp. 19-31, 2024, DOI:10.32604/chd.2024.046339

    Abstract Background: Given the pervasive issues of obesity and diabetes both in Puerto Rico and the broader United States, there is a compelling need to investigate the intricate interplay among body mass index (BMI), pregestational, and gestational maternal diabetes, and their potential impact on the occurrence of congenital heart defects (CHD) during neonatal development. Methods: Using the comprehensive System of Vigilance and Surveillance of Congenital Defects in Puerto Rico, we conducted a focused analysis on neonates diagnosed with CHD between 2016 and 2020. Our assessment encompassed a range of variables, including maternal age, gestational age, BMI,… More >

  • Open Access

    ARTICLE

    DeepSVDNet: A Deep Learning-Based Approach for Detecting and Classifying Vision-Threatening Diabetic Retinopathy in Retinal Fundus Images

    Anas Bilal1, Azhar Imran2, Talha Imtiaz Baig3,4, Xiaowen Liu1,*, Haixia Long1, Abdulkareem Alzahrani5, Muhammad Shafiq6

    Computer Systems Science and Engineering, Vol.48, No.2, pp. 511-528, 2024, DOI:10.32604/csse.2023.039672

    Abstract Artificial Intelligence (AI) is being increasingly used for diagnosing Vision-Threatening Diabetic Retinopathy (VTDR), which is a leading cause of visual impairment and blindness worldwide. However, previous automated VTDR detection methods have mainly relied on manual feature extraction and classification, leading to errors. This paper proposes a novel VTDR detection and classification model that combines different models through majority voting. Our proposed methodology involves preprocessing, data augmentation, feature extraction, and classification stages. We use a hybrid convolutional neural network-singular value decomposition (CNN-SVD) model for feature extraction and selection and an improved SVM-RBF with a Decision Tree More >

  • Open Access

    ARTICLE

    A Robust Framework for Multimodal Sentiment Analysis with Noisy Labels Generated from Distributed Data Annotation

    Kai Jiang, Bin Cao*, Jing Fan

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 2965-2984, 2024, DOI:10.32604/cmes.2023.046348

    Abstract Multimodal sentiment analysis utilizes multimodal data such as text, facial expressions and voice to detect people’s attitudes. With the advent of distributed data collection and annotation, we can easily obtain and share such multimodal data. However, due to professional discrepancies among annotators and lax quality control, noisy labels might be introduced. Recent research suggests that deep neural networks (DNNs) will overfit noisy labels, leading to the poor performance of the DNNs. To address this challenging problem, we present a Multimodal Robust Meta Learning framework (MRML) for multimodal sentiment analysis to resist noisy labels and correlate More >

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