Umar Isa Abdulkadir^*, Anil Fernando^*

Journal on Artificial Intelligence, Vol.6, pp. 71-83, 2024, DOI:10.32604/jai.2024.045332

Abstract One of the significant issues the insurance industry faces is its ability to predict future claims related to individual policyholders. As risk varies from one policyholder to another, the industry has faced the challenge of using various risk factors to accurately predict the likelihood of claims by policyholders using historical data. Traditional machine-learning models that use neural networks are recognized as exceptional algorithms with predictive capabilities. This study aims to develop a deep learning model using sequential deep regression techniques for insurance claim prediction using historical data obtained from Kaggle with 1339 cases and eight variables. This study adopted a… More >

PEI QIN^#, MIAO LIU^#, XIN WANG, JIANHUA MA^*

BIOCELL, Vol.48, No.3, pp. 513-523, 2024, DOI:10.32604/biocell.2023.045640

Abstract Background: L-dopa (Levodopa) is well known for managing PD (Parkinson’s disease); however, its prolonged use caused dyskinesia (LID). Due to the varied presentation of LID, effective treatment options are scarce. Flavonoids reported their neuroprotective activity by ameliorating acetylcholinesterase, monoamine oxidase, and neuroinflammation. Kaempferol is another flavonoid bearing these potentials. Aim: To evaluate neuroprotective activity of kaempferol in dyskinetic rats. Methods: PD was developed in Sprague-Dawley rats by injecting combination of L-ascorbic acid (10 µL) + 6-OHDA (12 µg) in medial forebrain bundle to induce neuronal damage in substantial nigra (SNr). LID was induced by administrating combination of L-dopa (20 mg/kg)… More > Graphic Abstract

DIEGO HERNANDEZ^1,*, CHIH-YUAN CHENG^1,2, KARLA HERNANDEZ-VILLAFUERTE¹, MICHAEL SCHLANDER^1,2

Oncology Research, Vol.30, No.4, pp. 173-185, 2022, DOI:10.32604/or.2022.027262

Abstract Lung cancer is the most common cancer type worldwide and has the highest and second highest mortality rate for men and women respectively in Germany. Yet, the role of comorbid illnesses in lung cancer patient prognosis is still debated. We analyzed administrative claims data from one of the largest statutory health insurance (SHI) funds in Germany, covering close to 9 million people (11% of the national population); observation period was from 2005 to 2019. Lung cancer patients and their concomitant diseases were identified by ICD-10-GM codes. Comorbidities were classified according to the Charlson Comorbidity Index (CCI). Incidence, comorbidity prevalence and… More >