XIAOMEI HAN^#, SHUYING ZHANG^#, YIFU WANG, CHANGE QI, PENGNYU GUO, YALI XU, GUANGHUI LYU^*

BIOCELL, Vol.45, No.6, pp. 1509-1519, 2021, DOI:10.32604/biocell.2021.09506 - 01 September 2021

Abstract Diabetes Mellitus is a systematic disease with complications in multi-organs, including decreased implant osseointegration and a high failure rate of dental transplants. Accumulating evidence indicates that the signaling pathway directly impacts the process of bone metabolism and inflammatory response implicated with dental implants in diabetic patients. This review summarizes the recent advance in signaling pathways regulate osseointegration and inflammatory response in dental transplantation, aiming to identify the potential therapeutic target to reduce the dental transplant failure in diabetes patients, with emphasis on the surface characteristics of the implant, inflammatory signaling, AMPK, PPARγ, WNT, ROS, and More >

Dilek Sarici¹, Mustafa Ali Akin¹, Selim Kurtoglu¹, Ali Yikilmaz², Sabahattin Muhtaroglu³, Mehmet Adnan Ozturk¹, Tamer Gunes¹, S. Umit Sarici⁴

European Cytokine Network, Vol.24, No.2, pp. 104-109, 2013, DOI:10.1684/ecn.2013.0339

Abstract Introduction: Adiponectin has important anti-inflammatory and anti-atherogenic effects. Although adiponectin and atherosclerosis correlate inversely in children and adults, we have little information regarding this relationship in neonates. Methods: We measured cord blood adiponectin levels and abdominal aortic intima media thickness (aIMT) in 80 healthy, term neonates and investigated the relationship between adiponectin and total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), and triglyceride, and their relationships to infant anthropometry and gender. Results: Mean birth weight, length, head circumference and aIMT values for male neonates were statistically significantly higher than those for female neonates. Adiponectin levels were… More >

Victoria Perna¹, Antonio Pérez-Pérez¹, Patricia Fernández-Riejos¹, Juan Polo-Padillo², Nínive Batista³, Angel Domínguez-Castellano³, Víctor Sánchez-Margalet¹

European Cytokine Network, Vol.24, No.4, pp. 157-161, 2013, DOI:10.1684/ecn.2014.0346

Abstract An impaired immune response in tuberculosis patients seems to be related to weight loss that coexists with an immunoendocrine imbalance. Thus, wasting is well-recognised as a prominent feature of tuberculosis (TB), which may not be reversed even after six months of treatment. Adipokines may play a role in the immune response to M. tuberculosis, and TB may impair the expression of inflammatory adipokines, such as leptin. We aimed to study patients with pulmonary TB before and six months after treatment, by measuring plasma leptin, soluble leptin receptor and adiponectin, weight and body mass index. Nineteen patients… More >

Cihan Meral¹, Ferhat Cekmez², Sebahattin Vurucu², Emre Tascılar², Ozgur Pirgon¹, F. Emre Canpolat², Osman Metin Ipcioglu³, Gokhan Aydemir¹, Secil Aydınoz¹

European Cytokine Network, Vol.22, No.2, pp. 118-122, 2011, DOI:10.1684/ecn.2011.0284

Abstract Aim. To investigate the relationship between the newly discovered adipocytokines and increasing body weight (paralleled by increased insulin resistance), and antiepileptic drug therapy with valproic acid (VPA). Design and methods. 44 children with idiopathic, generalized epilepsy treated with valproic acid (VPA), and 40 control group children were included in this study. Results. Both the VPA-treated group and the control group showed no significant difference in terms of age, total cholesterol and LDL-cholesterol. Subjects in the VPA group had significantly higher BMI-SDS than control subjects (2.3±0.15 vs-0.04±0.8, p<0.001). HOMA-IR, apelin and visfatin levels were significantly increased More >

Rebecca L. O’Malley, Samir S. Taneja

Canadian Journal of Urology, Vol.13, Suppl.2, pp. 11-17, 2006

Abstract The relationship between obesity and prostate cancer is currently a hotly debated topic, but despite the number of publications devoted to the topic, the actual nature of the relationship remains uncertain. Obesity has been shown to have a direct relationship with the incidence of prostate cancer in a number of studies but an equal number of studies have shown no association. The relationship is further obscured with recent findings that obesity in younger obese men may actually be protective against prostate cancer. Confounding factors include the lack of correlation of body mass index (BMI) as… More >