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  • Open Access


    Exosomes from adipose tissue-derived stem/stromal cells: A key to future regenerative medicine


    BIOCELL, Vol.46, No.12, pp. 2701-2704, 2022, DOI:10.32604/biocell.2022.022229

    Abstract Advances in regenerative medicine correlate strongly with progress in the use of adipose tissue-derived mesenchymal stem/stromal cells. The range of therapeutic indications has also expanded over recent years. Numerous recent studies have highlighted the primary importance of paracrine secretion by these cells. Though it is interesting to compare the different types of such secretions, we believe that exosomes (extra-cellular vesicles possessing the same properties as their source cells) will likely be the main key in tomorrow’s cell therapy. Exosomes also have many advantages compared to the direct use of cells, making these particles a major target in fundamental and translational… More >

  • Open Access


    Adipose-derived mesenchymal stem/stromal cells: from the lab bench to the basic concepts for clinical translation

    Yesica Romina FRONTINI-LÓPEZ1, Aldana Daniela GOJANOVICH1, Diego MASONE1,2, Diego Martín BUSTOS1,3, Marina UHART1

    BIOCELL, Vol.42, No.3, pp. 67-78, 2018, DOI:10.32604/biocell.2018.07013

    Abstract In the last years, much work has shown that the most effective repair system of the body is represented by stem cells, which are defined as undifferentiated precursors that own unlimited or prolonged self-renewal ability, which also have the potential to transform themselves into various cell types through differentiation.All tissues that form the body contain many different types of somatic cells, along with stem cells that are called ‘mesenchymal stem (or stromal) cells’ (MSC). In certain circumstances, some of these MSC migrate to injured tissues to replace dead cells or to undergo differentiation to repair it.The discovery of MSC has… More >

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