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  • Open Access

    ARTICLE

    Health-Related Quality of Life, Emotional and Behavioral Problems in Children and Adolescents with Ebstein Anomaly

    Lianne M. Geerdink1,2,*, Malindi van der Mheen3,4, Gideon J. du Marchie Sarvaas5, Irene M. Kuipers6, Stefan Frerich7, Henriëtte ter Heide2, Willem A. Helbing8, Zina Feijzic1, Christian Schroer9, Chris L. de Korte10, Livia Kapusta1,11, Chris M. Verhaak12, Elisabeth M. W. J. Utens3,4

    Congenital Heart Disease, Vol.15, No.6, pp. 457-472, 2020, DOI:10.32604/CHD.2020.012994

    Abstract Background: Due to the improved survival rates of children and adolescents with congenital heart disease (CHD), more attention is now being directed towards their health-related quality of life (HRQoL), emotional and behavioral problems. Ebstein anomaly (EA) is a rare CHD with a broad clinical spectrum. The aim of the current study is to evaluate self- and proxy-reported HRQoL and emotional and behavioral problems in children and adolescents with EA. Methods: In this cross-sectional, multicenter study, we included EA patients (aged 8–17 years), who underwent routine clinical assessments in Dutch university hospitals between May 2017 and March 2019. The Generic Pediatric… More >

  • Open Access

    ARTICLE

    Anomaly Classification Using Genetic Algorithm-Based Random Forest Model for Network Attack Detection

    Adel Assiri*

    CMC-Computers, Materials & Continua, Vol.66, No.1, pp. 767-778, 2021, DOI:10.32604/cmc.2020.013813

    Abstract Anomaly classification based on network traffic features is an important task to monitor and detect network intrusion attacks. Network-based intrusion detection systems (NIDSs) using machine learning (ML) methods are effective tools for protecting network infrastructures and services from unpredictable and unseen attacks. Among several ML methods, random forest (RF) is a robust method that can be used in ML-based network intrusion detection solutions. However, the minimum number of instances for each split and the number of trees in the forest are two key parameters of RF that can affect classification accuracy. Therefore, optimal parameter selection is a real problem in… More >

  • Open Access

    ARTICLE

    Mid-Term Outcome of Surgical Treatment in Pediatric Patients with Ebstein’s Anomaly: A Single-Center Cohort Study

    Jiachen Li, Xianchao Jiang, Sim-eng Zhang, Jinyang Liu, Yajuan Zhang, Jun Yan, Shoujun Li, Qiang Wang*

    Congenital Heart Disease, Vol.15, No.5, pp. 387-397, 2020, DOI:10.32604/CHD.2020.013127

    Abstract Background: Ebstein’s anomaly (EA) is a malformation of the tricuspid valve (TV) and myopathy of the right ventricle (RV). Surgery is now the main treatment for the defect. Objective: To summarize our surgical results and experience based on patients with EA who were under 7 years of age and treated with different surgical treatments. Design: Single-center cohort study of Ebstein’s anomaly. Setting: China. Participants: 80 patients under 7 years old who were diagnosed of EA and underwent different surgical treatments were consecutively enrolled in our research from January 2010 to December 2019. Results: The median age of the 80 patients… More >

  • Open Access

    ARTICLE

    Comprehensive Long-Term Follow up of Adults with Arterial Switch Operation– European Collaboration for Prospective Outcome Research in Congenital Heart Disease (EPOCH-ASO)–Study Design and Protocols

    Francisco Javier Ruperti-Repilado1,#,*, Magalie Ladouceur2,#, Pastora Gallego3, Laura Dos4, Joaquin Rueda Soriano5, Berto Bouma6, Harald Gabriel7, Markus Schwerzmann1, Judith Bouchardy8,9, Daniel Tobler10,#, Matthias Greutmann11,#

    Congenital Heart Disease, Vol.15, No.5, pp. 309-338, 2020, DOI:10.32604/CHD.2020.012599

    Abstract Background: Long-term outcomes in adults with prior arterial switch operation (ASO) have not yet been well defined. The aim of this study is to elucidate incidence and predictors of adverse cardiac outcomes in a prospectively followed cohort of adults after their ASO. Methods: The comprehensive longterm follow up of adults with ASO is a project within the European collaboration for prospective outcome research in congenital heart disease (EPOCH). It is designed as a prospective, international multicenter cohort study. Consecutive patients (age ≥ 16 years) with prior ASO will be included at 11 European tertiary care centers. Participants will be followed… More >

  • Open Access

    ARTICLE

    The Design and Implementation of a Multidimensional and Hierarchical Web Anomaly Detection System

    Jianfeng Guan*, Jiawei Li, Zhongbai Jiang

    Intelligent Automation & Soft Computing, Vol.25, No.1, pp. 131-141, 2019, DOI:10.31209/2018.100000050

    Abstract The traditional web anomaly detection systems face the challenges derived from the constantly evolving of the web malicious attacks, which therefore result in high false positive rate, poor adaptability, easy over-fitting, and high time complexity. Due to these limitations, we need a new anomaly detection system to satisfy the requirements of enterprise-level anomaly detection. There are lots of anomaly detection systems designed for different application domains. However, as for web anomaly detection, it has to describe the network accessing behaviours characters from as many dimensions as possible to improve the performance. In this paper we design and implement a Multidimensional… More >

  • Open Access

    ARTICLE

    Long Term Follow-Up of Ebstein’s Anomaly—What to Expect in Adult Life?

    Tânia Branco Mano1,*, João Ferreira Reis1, Ana Figueiredo Agapito1, André Monteiro1, Mário Oliveira1, Luísa Moura Branco1, José Fragata2, Fátima Pinto3, Rui Cruz Ferreira1, Lídia de Sousa1

    Congenital Heart Disease, Vol.15, No.3, pp. 153-162, 2020, DOI:10.32604/CHD.2020.011500

    Abstract Introduction: Due to the low prevalence and wide variation of severity of Ebstein’s Anomaly (EA), long-term follow-up data are scarce. The aim was to evaluate the long-term outcome of an adult population with EA. Methods: Retrospective analysis of EA adults followed in the past 42 years in a tertiary congenital heart disease outpatient clinic. Predictors of complications and mortality were assessed. Results: We studied 53 patients: 53% females, mean age 46 ± 19 years, 36% cyanotic, 55% diagnosed at adult age. Tricuspid regurgitation was moderate or severe in 33% and 46%, respectively, and during follow-up (mean 12 ± 10… More >

  • Open Access

    ARTICLE

    Anomaly IoT Node Detection Based on Local Outlier Factor and Time Series

    Fang Wang1, *, Zhe Wei1, Xu Zuo2

    CMC-Computers, Materials & Continua, Vol.64, No.2, pp. 1063-1073, 2020, DOI:10.32604/cmc.2020.09774

    Abstract The heterogeneous nodes in the Internet of Things (IoT) are relatively weak in the computing power and storage capacity. Therefore, traditional algorithms of network security are not suitable for the IoT. Once these nodes alternate between normal behavior and anomaly behavior, it is difficult to identify and isolate them by the network system in a short time, thus the data transmission accuracy and the integrity of the network function will be affected negatively. Based on the characteristics of IoT, a lightweight local outlier factor detection method is used for node detection. In order to further determine whether the nodes are… More >

  • Open Access

    ARTICLE

    Performance Anomaly Detection in Web Services: An RNN- Based Approach Using Dynamic Quality of Service Features

    Muhammad Hasnain1, Seung Ryul Jeong2, *, Muhammad Fermi Pasha3, Imran Ghani4

    CMC-Computers, Materials & Continua, Vol.64, No.2, pp. 729-752, 2020, DOI:10.32604/cmc.2020.010394

    Abstract Performance anomaly detection is the process of identifying occurrences that do not conform to expected behavior or correlate with other incidents or events in time series data. Anomaly detection has been applied to areas such as fraud detection, intrusion detection systems, and network systems. In this paper, we propose an anomaly detection framework that uses dynamic features of quality of service that are collected in a simulated setup. Three variants of recurrent neural networks-SimpleRNN, long short term memory, and gated recurrent unit are evaluated. The results reveal that the proposed method effectively detects anomalies in web services with high accuracy.… More >

  • Open Access

    ARTICLE

    Surgical treatment of anomalous left main coronary artery with an intraconal course

    Richard D. Mainwaring, Frank L. Hanley

    Congenital Heart Disease, Vol.14, No.4, pp. 504-510, 2019, DOI:10.1111/chd.12826

    Abstract Objective: Anomalous left main coronary artery (LMCA) with an intraconal course is a relatively rare form of anomalous aortic origin of a coronary artery (AAOCA) from the wrong sinus of Valsalva. There is currently a paucity of information regarding this entity. The purpose of this article is to review our surgical experience with repair of anomalous LMCA with an intraconal course.
    Methods: This was a retrospective review of 12 patients with an anomalous LMCA and an intraconal course who underwent surgical repair. The median age at surgery was 15 years (range 2‐47). The seven oldest patients all had preoperative symptoms… More >

  • Open Access

    ARTICLE

    Contemporary outcomes and mortality risks of Ebstein anomaly: A single-center experience in Thailand

    Varisara Pornprasertchai, Chodchanok Vijarnsorn, Supaluck Kanjanauthai, Paweena Chungsomprasong, Prakul Chanthong, Kritvikrom Durongpisitkul, Jarupim Soongswang

    Congenital Heart Disease, Vol.14, No.4, pp. 619-627, 2019, DOI:10.1111/chd.12759

    Abstract Background: The increasing number of patients with Ebstein anomaly (EA) surviving into adulthood implies improvements in the treatments for the complex lesion. We revisited the clinical outcomes of patients with EA to demonstrate their “real world” survival.
    Objectives: To identify the survival and predictors of mortality in patients with EA who underwent medical or surgical management in the present era.
    Methods: All patients who had EA with atrioventricular concordance between 1994 and 2016 were retrospectively reviewed. Baseline characteristics, initial echocardio‐ graphic findings, treatments, and outcomes were explored. The survival analysis was performed at the end of 2017. A multivariate analysis… More >

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