Yiwen Li^1,#, Hongyan Si^1,#, Peng Wang¹, Hai Luo¹, Minggui Shen², Xiaoping Rao³, Zhanqian Song², Shibin Shang², Zongde Wang^1,*, Shengliang Liao^1,*

Journal of Renewable Materials, Vol.12, No.1, pp. 45-56, 2024, DOI:10.32604/jrm.2023.031089

Abstract Turpentine is a renewable and resourceful forest product. The deep processing and utilization of turpentine, particularly its primary component β-pinene, has garnered widespread attention. This study aimed to synthesize 40 derivatives of β-pinene, including nopinone, 3-cyanopyridines of nopinone, myrtanyl acid, myrtanyl acylthioureas, and myrtanyl amides. We assessed the antiviral activities of these β-pinene derivatives against influenza virus A/Puerto Rico/8/34 (H1N1) using the 3-(4,5-dimetylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method. The β-pinene derivatives were used before and after cellular infection with the influenza virus to evaluate their preventive and therapeutic effects against the H1N1 virus. The results showed that only compound 10o exhibited a preventive… More > Graphic Abstract

Chel-Guerrero LD¹, R Gómez-Cansino², SL Gúzman-Gutierrez³, MG Campos-Lara⁴, E Saury-Duch¹, F Díaz de León Sánchez⁵, R Reyes-Chilpa⁶, JA Mendoza-Espinoza⁷

Phyton-International Journal of Experimental Botany, Vol.87, pp. 68-71, 2018, DOI:10.32604/phyton.2018.87.068

Abstract The objective of this study was to investigate extracts from the peels of Annona squamosa L. (purple sugar apple), Annona reticulata L. (custard apple), Chrysophyllum cainito L. (green star apple), and Melicoccus bijugatus Jacq. (mamoncillo), as potential sources of anti-HIV-1 agents. Methanolic extracts from the peels of the aforementioned tropical fruits were obtained by maceration. Antiviral activity was evaluated through HIV-1 RT inhibition by extracts, using a non-radioactive immuno/colorimetric assay (Lenti RT Activity Assay, Cavidi Tech). Assay was performed according to the protocol provided by the manufacturer. Extracts from the peels of A. squamosa, A. reticulata, and C. cainito showed… More >