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    REVIEW

    Apigenin as a promising myocyte protectant against damage and degradation

    XIAO HUANG1,2,3,#,*, ZHIHAI YU4,#, LIJUAN NING5, YU LEI5, XUEFEI ZHANG5, ZHUYING WANG2,*

    BIOCELL, Vol.46, No.2, pp. 383-388, 2022, DOI:10.32604/biocell.2021.015651

    Abstract Myocytes power the movement of all organs in the body. Damage to and degradation of myocytes causes hypokinesia and muscle-related degenerative diseases. Apigenin, a kind of flavone, is being used to treat many disorders. It exerts a host of different pharmacological activities, such as anti-inflammatory, anti-mutagenic, cardioprotective, and antioxidant effects. Accordingly, apigenin is considered a promising candidate for myocyte protection. In this review, we introduced the characteristics of apigenin. The means of apigenin protection of myocytes as well as the mechanism were summarized and discussed. The protective effects can be classified into proliferation-promoting, anti-inflammatory, atrophy-preventing, metabolism-increasing, and antioxidative effects. Additionally,… More >

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