Wenjia Wang1, 2, Xiuqing Qian1, 2, Qi Li1, 2, Gong Zhang1, 2, Huangxuan Zhao1, 2, Tan Li1, 2, Yang Yu1, 2, Hongfang Song1, 2, *, Zhicheng Liu1, 2, *
Molecular & Cellular Biomechanics, Vol.16, No.1, pp. 59-74, 2019, DOI:10.32604/mcb.2019.06393
Abstract Pupillary block is considered as an important cause of primary angle-closure glaucoma (PACG). In order to investigate the effect of pupillary block on the hydrodynamics of aqueous humor (AH) in anterior chamber (AC) and potential risks, a 3D printed eye model was developed to mimic the AH flow driven by fluid generation, the differential pressure between AC and posterior chambers (PC) and pupillary block. Particle image velocimetry technology was applied to visualize flow distribution. The results demonstrated obvious differences in AH flow with and without pupillary block. Under the normal condition (without pupillary block), the flow filed of AH was… More >
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