Agustín Pérez-Londoño, Alejandro Abello, Boris Gershman, Ruslan Korets

Canadian Journal of Urology, Vol.31, No.2, pp. 11848-11853, 2024

Abstract Holmium laser enucleation of the prostate (HoLEP) is considered a size-independent technique to treat benign prostatic hyperplasia. This safe and effective procedure is increasingly being adopted in urology training programs worldwide, yet limited teaching strategies have been described. Endoscopic handling during HoLEP allows for a simultaneous interaction between the surgeon and trainee, facilitating a guided teaching strategy with increasing difficulty as experience grows. In this article, we describe our stepwise approach for teaching HoLEP as part of a structured surgical training curriculum. We also evaluate the association of our method with intraoperative efficiency parameters and More >

Bruce M. Gao, Seyedamirvala Saadat, Edward J. H. Choi, James Jiang, Akhil K. Das

Canadian Journal of Urology, Vol.31, No.3, pp. 11904-11907, 2024

Abstract Holmium enucleation of the prostate (HoLEP) is a gold standard, size-independent surgical treatment for benign prostatic hyperplasia (BPH) distinguished for its efficacy in tissue removal, shorter catheterization durations, lower transfusion rates, and decreased hospital stays when compared to transurethral resection of the prostate (TURP). The objective of this article is to demonstrate the step-by-step procedure of holmium laser cystolitholapaxy and enucleation of the prostate for BPH, emphasizing a top-down modified two-lobe technique with early apical release which enhances visualization and irrigation flow during the enucleation process. More >

Congenital Heart Disease, Vol.19, Suppl.1, pp. 1-55, 2024

Abstract This article has no abstract. More >

Tao Yan¹, Javed Rashid^2,3, Muhammad Shoaib Saleem^3,4, Sajjad Ahmad⁴, Muhammad Faheem^5,*

CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 2685-2708, 2024, DOI:10.32604/cmc.2024.058186 - 18 November 2024

Abstract Electricity is essential for keeping power networks balanced between supply and demand, especially since it costs a lot to store. The article talks about different deep learning methods that are used to guess how much green energy different Asian countries will produce. The main goal is to make reliable and accurate predictions that can help with the planning of new power plants to meet rising demand. There is a new deep learning model called the Green-electrical Production Ensemble (GP-Ensemble). It combines three types of neural networks: convolutional neural networks (CNNs), gated recurrent units (GRUs), and… More >

HYUNHO KIM¹, UIJU CHO², SOOK HEE HONG³, HYUNG SOON PARK¹, IN-HO KIM³, HO JUNG AN¹, BYOUNG YONG SHIM¹, JIN HYOUNG KANG^3,*

Oncology Research, Vol.32, No.6, pp. 1021-1030, 2024, DOI:10.32604/or.2024.048919 - 23 May 2024

Abstract Background: Apolipoprotein B mRNA editing catalytic polypeptide (APOBEC), an endogenous mutator, induces DNA damage and activates the ataxia telangiectasia and Rad3-related (ATR)-checkpoint kinase 1 (Chk1) pathway. Although cisplatin-based therapy is the mainstay for muscle-invasive bladder cancer (MIBC), it has a poor survival rate. Therefore, this study aimed to evaluate the efficacy of an ATR inhibitor combined with cisplatin in the treatment of APOBEC catalytic subunit 3B (APOBEC3B) expressing MIBC. Methods: Immunohistochemical staining was performed to analyze an association between APOBEC3B and ATR in patients with MIBC. The APOBEC3B expression in MIBC cell lines was assessed… More >

Puja S. Prasad¹, Adepu Sree Lakshmi¹, Sandeep Kautish², Simar Preet Singh³, Rajesh Kumar Shrivastava³, Abdulaziz S. Almazyad⁴, Hossam M. Zawbaa⁵, Ali Wagdy Mohamed^6,7,*

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 725-739, 2024, DOI:10.32604/cmes.2023.030640 - 30 December 2023

Abstract Pupil dynamics are the important characteristics of face spoofing detection. The face recognition system is one of the most used biometrics for authenticating individual identity. The main threats to the facial recognition system are different types of presentation attacks like print attacks, 3D mask attacks, replay attacks, etc. The proposed model uses pupil characteristics for liveness detection during the authentication process. The pupillary light reflex is an involuntary reaction controlling the pupil’s diameter at different light intensities. The proposed framework consists of two-phase methodologies. In the first phase, the pupil’s diameter is calculated by applying… More >

Matt S. Ashley¹, Jason Phillips², Gregg Eure³

Canadian Journal of Urology, Vol.30, No.2, pp. 11509-11515, 2023

Abstract Millions of men in North America suffering from lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are managed on medical therapy. Most patients, however, report poor adherence, and yet relatively few pursue more definitive surgical solutions. The Prostatic Urethral Lift (PUL) was designed to address many of the patient-identified barriers to surgery, namely iatrogenic sexual dysfunction, incontinence, lengthy recovery and postoperative catheterization. Randomized studies and large real world multicenter and database studies have demonstrated safety and effectiveness of PUL when addressing lateral lobe disease. In recent years further technique and device development… More >

Sagar R. Patel, Katherine A. Lowrey, Angeline Johny, Christopher P. Smith

Canadian Journal of Urology, Vol.30, No.4, pp. 11619-11623, 2023

Abstract Introduction: Prostatic urethral lifts (PUL) provide improvement in urinary symptoms for men with benign prostatic hyperplasia (BPH). The aim of this study is to determine operative factors associated with improvement in urinary symptoms after PUL in men with bothersome BPH.
Materials and methods: Men with BPH undergoing PUL at a single, tertiary center were identified from 2019 to 2022. Inclusion criteria included documented prostate volume as well as preoperative and postoperative cystoscopic images of the prostatic urethra. Multivariate regression modeling was performed to determine the predictive factors—including prostate volume, number of implants, and degree of unobstructed prostatic… More >

Kenneth M. Kernen¹, Shalina Omar², Bradley Goodnight², Paul Skodny³, Stuart Bruce³, Tiffany M. Yu²

Canadian Journal of Urology, Vol.30, No.5, pp. 11676-11685, 2023

Abstract Introduction: To evaluate the safety and efficacy of the temporarily implanted nitinol device (iTind) versus prostatic urethral lift (PUL) for minimally invasive surgical treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia in a matching-adjusted indirect comparison (MAIC).
Materials and methods: Seven clinical trials were identified via a systematic literature review. Individual patient data from iTind trials and aggregated data from PUL trials were used in the MAIC. Safety and efficacy outcomes at 12 months post-treatment were compared between the adjusted iTind population and the pooled PUL population.
Results: iTind patients were significantly less likely than… More >

Kussil Oumedjbeur¹, Nicholas J. Corsi², David Bouhadana³, Ahmed Ibrahim⁴, David-Dan Nguyen⁵, Imad Matta⁴, Adel Arezki³, Iman Sadri³, Tawfik Elsherbini⁶, Naeem Bhojani⁴, Dean S. Elterman⁵, Bilal Chughtai⁷, Brian T. Helfand⁸, Alexander P. Glaser⁸, Vincent Misrai⁹, Steven Kaplan¹⁰, Peter Gilling¹¹, Neil Barber¹², Mihir Desai¹³, Gopal H. Badlani¹⁴, Alexis E. Te⁷, Claus G. Roehrborn¹⁵, Kevin C. Zorn⁴

Canadian Journal of Urology, Vol.30, No.5, pp. 11650-11658, 2023

Abstract Introduction: To report the 5-year efficacy and safety of Aquablation compared with transurethral resection of the prostate for the management of lower urinary tract symptoms secondary to benign prostatic hyperplasia in men with prostate volumes 50-80 mL.
Materials and methods: In a large double-blinded, multicenter, and prospective randomized controlled trial, 96 randomized men with 50-80 mL prostates who underwent Aquablation or transurethral prostate resection were prospectively identified for subgroup analysis. Follow up was performed for up to 5 years. The primary efficacy endpoint was the reduction in International Prostate Symptom Score (IPSS) at 6 months. The primary… More >