Chunliu He1, Jiaqiu Wang2, Yuxiang Huang1, Tongjing Zhu1, Yuehong Miao1, Zhiyong Li1,2*
Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 23-36, 2016, DOI:10.3970/mcb.2016.013.027
Abstract Fibrous cap thickness (FCT) is seen as critical to plaque vulnerability. Therefore, the development of automatic algorithms for the quantification of FCT is for estimating cardiovascular risk of patients. Intravascular optical coherence tomography (IVOCT) is currently the only in vivo imaging modality with which FCT, the critical component of plaque vulnerability, can be assessed accurately. This study was aimed to discussion the correlation between the texture features of OCT images and the FCT in lipid-rich atheroma. Methods: Firstly, a full automatic segmentation algorithm based on unsupervised fuzzy c means (FCM) clustering with geometric constrains was developed to segment the ROIs… More >
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