QIAN ZHANG1,#, MIN ZHEN2,#, PENG LI3, XIAOPEI CHI4,*, YIFEI ZHANG1,*
BIOCELL, Vol.47, No.2, pp. 431-439, 2023, DOI:10.32604/biocell.2023.024948
Abstract The correlation between microbiota plays a vital role in the progression of periodontal disease. This study investigated the in situ interaction networks between periodontal pathogens in periodontal and peri-implant disease. We used quantitative real-time polymerase chain reaction and Pearson’s correlation coefficients to quantify the copy numbers and correlations of four oral core species—Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella intermedia, and Streptococcus gordonii—from 80 subgingival sites (healthy and with periodontitis or gingivitis) in patients with periodontitis, and 68 subgingival sites (healthy and with periodontitis, gingivitis, peri-implantitis, or peri-implant mucositis) in patients with implants. The highest bacterial counts were observed for Porphyromonas gingivalis… More >
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