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    REVIEW

    The bacteriophage mu lysis system–A new mechanism of host lysis?

    SAIKAT SAMANTA1,#, ASHISH RANJAN SHARMA2,#, ABINIT SAHA1, MANOJ KUMAR SINGH1, ARPITA DAS1, MANOJIT BHATTACHARYA3, RUDRA PRASAD SAHA1,*, SANG-SOO LEE2,*, CHIRANJIB CHAKRABORTY1,*

    BIOCELL, Vol.45, No.5, pp. 1175-1186, 2021, DOI:10.32604/biocell.2021.015537

    Abstract Bacteriophages are viruses that infect bacteria and can choose any one of the two alternative pathways for infection, i.e., lysis or lysogeny. Phage lysis is one of the conventional biological processes required to spread infection from one bacterium to another. Our analysis suggests that in the paradigm bacteriophage Mu, six proteins might be involved in host cell lysis. Mu has a broad host range, and Mu-like phages were found in both Gram-negative and Gram-positive bacteria. An analysis of the genomes of Mu and Mu-like phages could be useful in elucidating the lysis mechanism in this group of phages. A detailed… More >

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