GANG WANG#, MINGPING QIAN#, WEI JIAN, JUHANG CHU, YIXIANG HUANG*
Oncology Research, Vol.31, No.1, pp. 63-70, 2023, DOI:10.32604/or.2022.028168
Abstract Circular RNA (circRNA), as a newly discovered non-coding RNA with important regulatory potential, is closely
related to the occurrence and progression of various tumors. This study aimed to investigate has_circ_0000069 expression
in breast cancer and its influence on cellular activities. Using real-time quantitative polymerase chain reaction,
has_circ_0000069 levels were measured in 137 pairs of tissue specimens, as well as cancer cell lines. The cellular
activities of cell lines were determined by cell counting kit-8 (CCK-8) and Transwell assays. The potential targeting
miRNAs were predicted and verified using an online database and dual-luciferase reporter assay. Has_circ_0000069
was highly expressed in breast… More >
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