IVANA SAMARŽIJA1,2,*
BIOCELL, Vol.46, No.7, pp. 1747-1750, 2022, DOI:10.32604/biocell.2022.018784
Abstract Comparisons of gene expression profiles between primary tumors and metastasis have revealed genes that are
implicated in metastasis formation. However, gene expression studies conducted on metastasis samples from the same
primary site usually do not discriminate between different secondary sites. Although the change in the expression of
number of genes is expected to be common to metastasis from the same primary but different secondary sites, herein
the data that point to substantial differences are presented. Furthermore, the reciprocal communication between
metastatic and host cells that is influencing these differences is outlined to emphasize the need for stratification of
metastasis samples… More >
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