FABIANO BINI1,*, ANDRADA PICA1, ANDREA MARINOZZI2, FRANCO MARINOZZI1
BIOCELL, Vol.46, No.10, pp. 2225-2229, 2022, DOI:10.32604/biocell.2022.021150
Abstract Bone tissue is a hierarchical material characterized at nanoscale by the mineralized collagen fibril, a recurring
structure mainly composed of apatite minerals, collagen and water. Bone nanostructure has a fundamental role in
determining the mechanical behavior of the tissue and its mass transport properties. Diffusion phenomenon allows to
maintain an adequate supply of metabolites in the mechanisms of bone remodeling, adaptation and repair. Several
analytical and computational models have been developed to analyze and predict bone tissue behavior. However, the
fine replication of the natural tissue still represents a challenge. Insights on the structural organization at nanoscale
and on the… More >
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