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  • Open Access

    ARTICLE

    IDV: Internet Domain Name Verification Based on Blockchain

    Ning Hu1, Yu Teng2, Yan Zhao1, Shi Yin1, Yue Zhao3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.1, pp. 299-322, 2021, DOI:10.32604/cmes.2021.016839

    Abstract The rapid development of blockchain technology has provided new ideas for network security research. Blockchain-based network security enhancement solutions are attracting widespread attention. This paper proposes an Internet domain name verification method based on blockchain. The authenticity of DNS (Domain Name System) resolution results is crucial for ensuring the accessibility of Internet services. Due to the lack of adequate security mechanisms, it has always been a challenge to verify the authenticity of Internet domain name resolution results. Although the solution represented by DNSSEC (Domain Name System Security Extensions) can theoretically solve the domain name verification problem, it has not been… More >

  • Open Access

    ARTICLE

    Place des CTC et de l’ADN circulant dans la prise en charge du cancer du sein
    CTC and cDNA in Breast Cancer Management

    V. Allouchery, L. Augusto, F. Clatot

    Oncologie, Vol.21, No.1, pp. 40-48, 2019, DOI:10.3166/onco-2019-0035

    Abstract It has been known for a long time that circulating tumor cells (CTC) as well as circulating tumor DNA (ctDNA) can be detected. However, only recent technical advances allowed evaluating the interest of CTC and ctDNA in breast cancer. In both early and metastatic breast cancers, CTC detection is a recognized factor for poor outcome. Nevertheless, CTC detection does not impact cancer management yet. The use of ctDNA in daily practice will require validation by prospective data. But ctDNA seems particularly promising both for residual disease evaluation and identification of tumor clones harbouring mutations (PI3KC, ESR1) and may predict efficacy… More >

  • Open Access

    ARTICLE

    Molecular cloning and characterization of a novel mannosebinding lectin cDNA from Zantedeschia aethiopica

    ZHONGHAI CHEN1, YONGZHEN PANG1, XIAOJUN LIU1, XINGLONG WANG1, ZHONGXIANG DENG1, XIAOFEN SUN1, KEXUAN TANG1,2

    BIOCELL, Vol.29, No.2, pp. 187-193, 2005, DOI:10.32604/biocell.2005.29.187

    Abstract Using RNA extracted from Zantedeschia aethiopica young leaves and primers designed according to the conservative regions of Araceae lectins, the full-length cDNA of Z. aethiopica agglutinin (ZAA) was cloned by rapid amplification of cDNA ends (RACE). The full-length cDNA of zaa was 871 bp and contained a 417 bp open reading frame (ORF) encoding a lectin precursor of 138 amino acids. Through comparative analysis of zaa gene and its deduced amino acid sequence with those of other Araceae species, it was found that zaa encoded a precursor lectin with signal peptide. Secondary and three-dimensional structure analyses showed that ZAA had… More >

  • Open Access

    ARTICLE

    RNA fingerprinting using RAP-PCR identifies an EBAF homologue mRNA differentially expressed in rat oviduct

    PABLO A. VALDECANTOS, MARTÍN E. ARGAÑARAZ, CARLOS M. ABATE, DORA C. MICELI

    BIOCELL, Vol.28, No.3, pp. 287-297, 2004, DOI:10.32604/biocell.2004.28.287

    Abstract As a step towards the identification of genes preferentially expressed in the oviduct during early rat embryo development, we isolated a cDNA fragment (Pr14) by using RNA arbitrarily primed PCR (RAP-PCR), being its expression restricted to oviduct and uterus; its mRNA is mainly expressed in oviduct during late luteal phase and early pregnancy. This fragment is 100% identical to a rat DNA sequence (Accession No. NW_047400) downstream the terminal exon of a Rattus norvegicus gene (Locus Link Accession No. LOC289316) similar to ebaf (endometrial bleeding-associated factor), a novel member of the Transforming Growth Factor superfamily. Northern analyses showed that this… More >

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