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Search Results (7)
  • Open Access

    ARTICLE

    L’engagement en matière de préservation de la qualité de vie des patients atteints de cancer : l’exemple des RCSF — Rencontres annuelles cancer sexualité et fertilité

    F. Farsi, E. Huyghe, L. Vanlemmens, S. Dolbeault, T. Almont, E. Marx, I. Flandrin, J. Véronique-Baudin, B. Panes-Ruedin, P. Bondil

    Psycho-Oncologie, Vol.17, No.2, pp. 99-104, 2023, DOI:10.3166/pson-2022-0235

    Abstract L’abord systématisé et en routine de la préservation de la vie intime, de la sexualité et de la fertilité n’est pas encore pleinement intégré à la consultation des praticiens et pas de manière significative par les autres intervenants du parcours de soins en cancérologie. On sait pourtant, et de manière de plus en plus documentée, que ce sont des sujets de préoccupation pour les patients et leurs partenaires, qui considèrent, pour leur grande majorité, que leur santé sexuelle et/ou leurs projets parentaux sont des sujets importants. Depuis maintenant plus de dix ans, un groupe d’experts nationaux (GEX–Groupe d’experts oncosexualité/oncofertilité de… More >

  • Open Access

    ARTICLE

    Hybrid GrabCut Hidden Markov Model for Segmentation

    Soobia Saeed1,*, Afnizanfaizal Abdullah1, N. Z. Jhanjhi2, Mehmood Naqvi3, Mehedi Masud4, Mohammed A. AlZain5

    CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 851-869, 2022, DOI:10.32604/cmc.2022.024085

    Abstract Diagnosing data or object detection in medical images is one of the important parts of image segmentation especially those data which is less effective to identify in MRI such as low-grade tumors or cerebral spinal fluid (CSF) leaks in the brain. The aim of the study is to address the problems associated with detecting the low-grade tumor and CSF in brain is difficult in magnetic resonance imaging (MRI) images and another problem also relates to efficiency and less execution time for segmentation of medical images. For tumor and CSF segmentation using trained light field database (LFD) datasets of MRI images.… More >

  • Open Access

    ARTICLE

    GM-CSF-Loaded Nanoparticles for Photothermal-Assisted Immunotherapy against Orthotopic Bladder Cancer

    Weifeng Ren1,2,#, Xiaomeng Cai2,3,#, Jun Chen2,3,#, Lifo Ruan2,3, Huiru Lu2, Jiayu Zhang2,3, Yi Hu2,3,*, Jimin Gao1,*

    Oncologie, Vol.23, No.3, pp. 359-371, 2021, DOI:10.32604/Oncologie.2021.018605

    Abstract This study reported the construction of GM-CSF-loaded chitosan/graphene oxide nanoparticles for photothermal therapy-assisted immunotherapy against murine orthotopic bladder cancer. The encapsulated GM-CSF in chitosan/graphene oxide nanoparticles facilitated their immobilization on biotinylated mouse orthotopic bladder cancer surface, resulting in slow release of antitumor immune adjuvant. Locally released GM-CSF efficiently recruited dendritic cells to bladder tumor sites, thereby promoting immune responses in mice. Thus, the activated immune response in mice provided enhanced antitumor effects. Meanwhile, the thermal effect from the nanoparticles upon light irradiation induced a significant increase in dendritic cells and T cells compared with other groups, which confirmed that the… More >

  • Open Access

    ARTICLE

    NFAT regulates CSF-1 gene transcription triggered by L-selectin crosslinking

    CUIXIA CHEN1*, LINGLING CUI2, XIN SHANG2, XIANLU ZENG2

    BIOCELL, Vol.34, No.2, pp. 57-64, 2010, DOI:10.32604/biocell.2010.34.057

    Abstract L-selectin is a member of the selectin family that play an important role both in mediating the initial capture and subsequent rolling of leukocytes along the endothelial cells. Furthermore, L-selectin can function as a signal molecule. In our previous studies, we reported that L-selectin ligation could regulate CSF-1 (colony-stimulating factor-1) gene transcription, in which AP-1 acts as a crucial transcriptional factor. Here we investigated the function of the NFAT in the CSF-1 gene transcriptional events. We found that overexpression of WT NFAT induce CSF-1 gene transcription greatly in the activated Jurkat cells. Furthermore, we found that NFAT can be recruited… More >

  • Open Access

    ARTICLE

    On the Modeling of Surface Tension and its Applications by the Generalized Interpolation Material Point Method

    L. Chen1 J. H. Lee1, C.-f. Chen1

    CMES-Computer Modeling in Engineering & Sciences, Vol.86, No.3, pp. 199-224, 2012, DOI:10.3970/cmes.2012.086.199

    Abstract This paper presents a numerical procedure to model surface tension using the Generalized Interpolation Material Point (GIMP) method which employs a background mesh in solving the equations of motion. The force due to surface tension is formulated at the mesh grid points by using the continuum surface force (CSF) model and then added to the equations of motion at each grid point. In GIMP, we use the grid mass as the color function in CSF and apply a moving average smoothing scheme to the grid mass to improve the accuracy in calculating the surface interface. The algorithm, named as GIMP-CSF,… More >

  • Open Access

    ARTICLE

    Modified Algorithm for Surface Tension with Smoothed Particle Hydrodynamics and Its Applications

    H.F.Qiang1, F.Z.Chen1, W.R. Gao1

    CMES-Computer Modeling in Engineering & Sciences, Vol.77, No.3&4, pp. 239-262, 2011, DOI:10.3970/cmes.2011.077.239

    Abstract Based on smoothed particle hydrodynamics (SPH) method with surface tension proposed by Morris, this paper is intended to modify equations for surface tension by modifying normal and curvature with corrective smoothing particle method (CSPM). Compared with the continuum surface force (CSF) model for surface tension employed in the traditional SPH method, the accuracy in the present paper is much higher in terms of handling the problems with large deformation and surface tension. The reason is that in the traditional SPH method the deficiency of particles is near the boundary and sharp-angled areas, and it causes gross errors of curvature calculation.… More >

  • Open Access

    ARTICLE

    Numerical Analysis on Unsteady Internal Flow in an Evaporating Droplet

    Zhentao Wang1,*, Kai Dong, Shuiqing Zhan

    FDMP-Fluid Dynamics & Materials Processing, Vol.13, No.4, pp. 221-234, 2017, DOI:10.3970/fdmp.2017.013.221

    Abstract We have investigated the unsteady internal flow occurring in an evaporating droplet interacting with a high-temperature atmospheric environment. The Navier-Stokes equations for both the liquid and the gas phases have been solved numerically in the framework of a Volume of Fluid (VOF) method relying on the so-called Continuum Surface Force (CSF) model. A specific kernel able to account for evaporation and related phase change has been incorporated directly in the VOF approach. The temperature distributions within the droplet has been found to be relatively uniform by virtue of the Marangoni flow. The transient evolution of the flow pattern and related… More >

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