JIAHAO ZHANG1,2,3, JIE REN4, ZIRUI LI1,2,3,*, YIXING GOU1,2,3,*
BIOCELL, Vol.47, No.7, pp. 1439-1447, 2023, DOI:10.32604/biocell.2023.028628
Abstract Circulating tumor cells (CTCs) are essential biomarkers for liquid biopsies, which are important in the early screening, prognosis, and real-time monitoring of cancer. However, CTCs are less abundant in the peripheral blood of patients, therefore, their isolation is necessary. Recently, the use of microfluidics for CTC sorting has become a research hotspot owing to its low cost, ease of integration, low sample consumption, and unique advantages in the manipulation of micron-sized particles. Herein, we review the latest research on microfluidics-based CTC sorting. Specifically, we consider active sorting using external fields (electric, magnetic, acoustic, and optical tweezers) and passive sorting using… More >
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