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    REVIEW

    Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR): A critical overview on the most promising applications of molecular scissors in oral medicine

    MARCO TATULLO1,*, LUISA LIMONGELLI2, ROSA MARIA MARANO3, ALESSANDRA VALLETTA4, ANGELA TEMPESTA2, SANDRO RENGO4

    BIOCELL, Vol.46, No.8, pp. 1837-1842, 2022, DOI:10.32604/biocell.2022.020570

    Abstract The scientific community is continuously working to translate the novel biomedical techniques into effective medical treatments. CRISPR-Cas 9 system (Clustered Regularly Interspaced Short Palindromic Repeats-9), commonly known as the “molecular scissor”, represents a recently developed biotechnology able to improve the quality and the efficacy of traditional treatments, related to several human diseases, such as chronic diseases, neurodegenerative pathologies and, interestingly, oral diseases. Of course, dental medicine has notably increased the use of biotechnologies to ensure modern and conservative approaches: in this landscape, the use of CRISPR-Cas-9 system may speed and personalize the traditional therapies, ensuring a good predictability of clinical… More >

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