Ziyi Wang*, Xinyu Zhang*, Xuedong Zhang†, Xuedong Jiang‡, Wenya Li*
Oncology Research, Vol.28, No.9, pp. 913-927, 2020, DOI:10.3727/096504021X16310057751016
Abstract Long intergenic nonprotein-coding RNA 1703 (LINC01703) has diagnostic significance in lung adenocarcinoma. However, its specific roles in non-small cell lung cancer (NSCLC) and downstream mechanisms have
not been investigated. In the current study, we characterized the role of LINC01703 in NSCLC malignancy
and elucidated its detailed mechanism of action. LINC01703 expression was measured by qRT-PCR. The
regulatory effects of LINC01703 on the malignancy of NSCLC cells were assessed by multiple functional
experiments. The targeted interaction was confirmed by RNA immunoprecipitation and luciferase reporter
assays. Herein, overexpression of LINC01703 in NSCLC was indicated in the TCGA database and further
proven in… More >
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