HYEONG SIM CHOI¹, JEONG-KUI KU¹, SEONG-GYU KO², PIL-YOUNG YUN^1,3,*

Oncology Research, Vol.33, No.5, pp. 1217-1227, 2025, DOI:10.32604/or.2025.059791 - 18 April 2025

Abstract Background: Oral cancer remains a significant global health challenge, as it has high morbidity and mortality rates. Current treatments show limited efficacy and have severe side effects, prompting searches for new therapeutic agents. SH003, a traditional herbal formulation comprising Astragalus membranaceus, Angelica gigas, and Trichosanthes kirilowii, has demonstrated potential anticancer properties in previous studies. However, its specific efficacy against oral cancer and the role of its key components, particularly Cucurbitacin D, remain underexplored. Methods: The cytotoxic effects of SH003 and its major components—i.e., Cucurbitacin D, Decursin, Formononetin, and Nodakenin—were evaluated using 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT), Trypan Blue exclusion, and… More >

Abdullah A. Asiri¹, Toufique A. Soomro^2,3,*, Ahmed Ali⁴, Faisal Bin Ubaid⁵, Muhammad Irfan^6,*, Khlood M. Mehdar⁷, Magbool Alelyani⁸, Mohammed S. Alshuhri⁹, Ahmad Joman Alghamdi¹⁰, Sultan Alamri¹⁰

CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.1, pp. 255-287, 2025, DOI:10.32604/cmes.2025.061683 - 11 April 2025

Abstract Global mortality rates are greatly impacted by malignancies of the brain and nervous system. Although, Magnetic Resonance Imaging (MRI) plays a pivotal role in detecting brain tumors; however, manual assessment is time-consuming and susceptible to human error. To address this, we introduce ICA2-SVM, an advanced computational framework integrating Independent Component Analysis Architecture-2 (ICA2) and Support Vector Machine (SVM) for automated tumor segmentation and classification. ICA2 is utilized for image preprocessing and optimization, enhancing MRI consistency and contrast. The Fast-Marching Method (FMM) is employed to delineate tumor regions, followed by SVM for precise classification. Validation on More >

Zhengjing Shen^1,2,*, Fanqiang Kong¹, Yu Liu¹, Jilai Zeng¹, Wengang Yang¹, Jiangbo Wu^1,2

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.3, pp. 589-603, 2025, DOI:10.32604/fdmp.2024.058727 - 01 April 2025

Abstract Erosion in slurry pumps presents a persistent challenge in industrial applications. This study examines the erosion of the static components of a 150ZJ-C42 centrifugal slurry pump, currently in operation at a beneficiation plant, under varying particle conditions. Utilizing high-precision three-dimensional reverse engineering, the pump’s flow passage geometry was reconstructed to facilitate detailed erosion analysis. Focusing on the front and rear baffles of the pump chamber, as well as the volute, erosion patterns were analyzed for different particle volume concentrations and sizes. The results reveal that the highest erosion damage consistently occurs near the volute tongue,… More > Graphic Abstract

Xiuyun Liu¹, Jixia Sun², Feng Ming³, Minxiao Liu^2,*, Xinyu Wang², Yingjie Zhang^2,*

Phyton-International Journal of Experimental Botany, Vol.94, No.2, pp. 379-391, 2025, DOI:10.32604/phyton.2025.060726 - 06 March 2025

Abstract To study the main aroma components of Phalaenopsis orchid and their relationship with colors, 10 fragrant cultivars with different colors, like pink, rose, yellow, and purple, were used as samples in this experiment. Headspace-gas chromatography-mass spectrometry was used to determine the main components of floral fragrance and analyze the correlation between floral color and fragrance. The results showed that the main aroma components of the 10 fragrant cultivars of Phalaenopsis were alcohols, alkenes, esters, and benzene ring compounds, and the main aroma components of different cultivars were diverse. The main aroma components of yellow fragrant flowers… More >

Eman Alhomaidi¹, Aisha Umar^2,*, Mustansar Mubeen³, Laurent Dufossé⁴, Yasir Iftikhar^3,*, Arpita Das⁵, Soumya Ghosh⁶, Muhammad Sibt-e-Abbas⁷

Phyton-International Journal of Experimental Botany, Vol.94, No.2, pp. 407-420, 2025, DOI:10.32604/phyton.2025.058035 - 06 March 2025

Abstract Aspergillus species produce aflatoxins and raise concerns about food safety in departmental stores and manufacturing mills. To address the risks posed by aflatoxins, and to advise the public on the highest quality rice that serves as a nutritious food source, an inquiry following the guidelines outlined in both local and international standards of food safety for the presence of aflatoxins is an essential requirement. Therefore, 16 white rice samples were selected randomly from low/high socio-economic departmental stores from 16 different localities. Grind powdered rice filtrate was extracted using chloroform. The filtrate applied on TLC plates and… More > Graphic Abstract

Jichao Zhao^1,2, Xu Yan^1,2, Jing Sun^1,2,*, Sheng Li³

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.2, pp. 279-292, 2025, DOI:10.32604/fdmp.2025.060998 - 06 March 2025

Abstract Shale gas reservoirs typically contain numerous nanoscale pores, with pore size playing a significant role in influencing the gas behavior. To better understand the related mechanisms, this study employs the Gauge-GEMC molecular simulation method to systematically analyze the effects of various pore sizes (5, 10, 20, and 40 nm) on the phase behavior and dew point pressure of the shale gas reservoir components. The simulation results reveal that when pore sizes are smaller than 40 nm, the dew point pressure increases significantly as the pore size decreases. For instance, the dew point pressure in 5… More > Graphic Abstract

Yao Jin^1,2,*, Jie Zhao^1,2, Xiaozhe Tan^1,2, Linghou Miao^1,2, Wenxing Yu^1,2

Digital Engineering and Digital Twin, Vol.2, pp. 131-144, 2024, DOI:10.32604/dedt.2024.048142 - 31 December 2024

Abstract Substation siting is an important foundation and a key task in power system planning. The article is based on a three-dimensional GIS platform combined with an improved BP neural network algorithm and proposes a substation siting method that is more efficient, accurate and provides a better user experience. Firstly, the BP algorithm is enhanced to improve its convergence speed and computational efficiency for a more accurate and reasonable calculation of optimal site selection. Then, a 24-item selection index system with 7 categories is proposed, which provides quantifiable data support and an evaluation basis for substation… More >

Dongdong Gu^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.013403

Abstract In this presentation, we will report our recent research progress and prospect in the fields of laser additive manufacturing (AM) / 3D printing (3DP) of high-performance/multi-functional lightweight metallic components for aerospace applications. The innovative elements of AM including multi-material layout, innovative structural design, tailored printing process, and resultant high performance and multiple functions of components will be addressed. For a tailored printing process, some key scientific issues in AM process control deserve to be studied, including interaction of energy and printed matter, thermodynamic and dynamic behavior of printing, relationship of process parameters, microstructure and properties. More >

Zhancai Zhan¹, Penghang Ling¹, Wugui Jiang^1,*, Tao Chen¹, Qinghua Qin^2,3, Longhui Mao¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.011400

Abstract In the intricate and multi-physical process of Laser Powder Bed Fusion (LPBF), the microstructure significantly influences the performance of the resulting components, particularly evident in the manufacturing of thin-walled structures. In this paper, a prediction model of microstructure evolution coupled with 3D cellular automaton (CA) and finite element (FE) method for thin-walled components of GH4169 fabricated by LPBF is established. In this model, the multi-layer and multi-track temperature field within the interest region of thin-walled parts is simulated by the FE method. Subsequently, the temperature history is transferred to the CA model for predicting the… More >

Yunfei Li¹, Dongjiang Wu¹, Fangyong Niu^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012365

Abstract The plastic deformation assisted method plays a positive role in regulating the microstructure and mechanical properties of metal components in additive manufacturing. In this work, the effect of hammer forging force on the microstructure and mechanical properties of 316L stainless steel additive components were investigated by using synchronous-hammer-forging-assisted laser directed energy deposition method. The results show that when the hammer forging force is greater than 40 N, the grain refinement effect is obvious, the grain size decreases by more than 60 %, and the maximum strength of the polar diagram decreases by more than 75 More >