Chun Yang∗,†, Dalin Tang∗,‡, Shunichi Kobayashi§, Jie Zheng¶, Pamela K. Woodard§, Zhongzhao Teng*, Richard Bach||, David N. Ku∗∗
Molecular & Cellular Biomechanics, Vol.5, No.4, pp. 259-274, 2008, DOI:10.3970/mcb.2008.005.259
Abstract Many acute cardiovascular syndromes such as heart attack and stroke are caused by atherosclerotic plaque ruptures which often happen without warning. MRI-based models with fluid-structure interactions (FSI) have been introduced to perform flow and stress/strain analysis for atherosclerotic plaques and identify possible mechanical and morphological indices for accurate plaque vulnerability assessment. In this paper, cyclic bending was added to 3D FSI coronary plaque models for more accurate mechanical predictions. Curvature variation was prescribed using the data of a human left anterior descending (LAD) coronary artery. Five computational models were constructed based on ex vivo MRI human coronary plaque data to… More >
Login
Register
