Yang Li1, Xiuxian Liu2, Zhiyong Li2,*, Jiayi Tong1, Yi Feng1, Genshan Ma1, Chengxing Shen3, Naifeng Liu1
Molecular & Cellular Biomechanics, Vol.14, No.4, pp. 213-229, 2017, DOI:10.3970/mcb.2017.014.213
Abstract Coronary tortuosity is a common angiographic finding, but the hemodynamic significance of coronary tortuosity is largely unknown. The impact of coronary tortuosity on coronary pressure and wall shear stress is still unclear. We addressed this issue in the present experimental study. A distorted tube model connected to heart pumping machine was established to simulate the coronary circulation. The pressure of each point was measured with a coronary pressure guidewire. Influence of tortuosity angle and tortuosity number on local pressure was measured. Wall shear stress was calculated accordingly to the pressure of each point. Pressure distribution in this system was affected… More >
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