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    ARTICLE

    Identification of tumor-suppressor genes in lung squamous cell carcinoma through integrated bioinformatics analyses

    HENG LI1,#, YOUMING LEI3,#, GAOFENG LI1, YUNCHAO HUANG2,*

    Oncology Research, Vol.32, No.1, pp. 187-197, 2024, DOI:10.32604/or.2023.030656

    Abstract Lung cancer is a prevalent malignancy, and fatalities of the disease exceed 400,000 cases worldwide. Lung squamous cell carcinoma (LUSC) has been recognized as the most common pathological form of lung cancer. The comprehensive understanding of molecular features related to LUSC progression has great significance in LUSC prognosis assessment and clinical management. In this study, we aim to identify a panel of signature genes closely associated with LUSC, which can provide novel insights into the progression of LUSC. Gene expression profiles were retrieved from public resources including gene expression omnibus (GEO) and the cancer genome atlas (TCGA) database. Differentially expressed… More >

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