SARA SOLTANIAN¹, HELIA RIAHIRAD¹, ATHAREH PABARJA¹, MOHAMMAD REZA KARIMZADEH², KOLSOUM SAEIDI^3,4

BIOCELL, Vol.41, No.2-3, pp. 33-40, 2017, DOI:10.32604/biocell.2017.41.033

Abstract Cancer stem cells (CSCs) are a small subpopulation of cancer cells whose resistance to chemotherapy and radiotherapy plays a pivotal role in treatment failure, tumor recurrence and metastasis. Today, the ability of many phytochemicals in targeting of CSCs has been identified. Kaempferol is a plant phytoestrogen that was recognized as a useful agent for targeting cancer cells by apoptosis induction, cell cycle arrest and inhibition of angiogenesis, migration, and invasion of cancer cells. In this study, we compared the effect of docetaxel as a common breast cancer chemotherapy drug and kaempferol on MCF-7 breast CSCs. Results showed that both docetaxel… More >

Lamia Bouafif¹, Noureddine Ellouze²

Sound & Vibration, Vol.52, No.6, pp. 2-10, 2018, DOI:10.32604/sv.2018.02410

Abstract Sound indexing and segmentation of digital documents especially in the internet and digital libraries are very useful to simplify and to accelerate the multimedia document retrieval. We can imagine that we can extract multimedia files not only by keywords but also by speech semantic contents. The main difficulty of this operation is the parameterization and modelling of the sound track and the discrimination of the speech, music and noise segments. In this paper, we will present a Speech/Music/Noise indexing interface designed for audio discrimination in multimedia documents. The program uses a statistical method based on ANN and HMM classifiers. After… More >

Maximiliano GIRAUD-BILLOUD^1,2,*, Claudio M. FADER^1,3, Rocío AGÜERO², Fernando EZQUER⁴, Marcelo EZQUER⁴

BIOCELL, Vol.42, No.2, pp. 35-40, 2018, DOI:10.32604/biocell.2018.07010

Abstract Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated. In the present study, we evaluate the role of autophagy at early stages of DN, induced in type 2 diabetes mellitus (T2DM) mouse, and its association with proximal tubule membrane endocytic receptors, megalin and cubilin. In T2DM animals we observed a tubule-interstitial injury with significantly increased levels of urinary GGT and ALP, but an absence of tubulointerstitial fibrosis. Kidney proximal tubule cells of T2DM animals showed autophagic vesicles larger than those observed… More >

V. Mendez-Trujillo¹, B. Valdez-Salas², M. Carrillo-Beltran², M. A. Curiel-Alvarez², O. Tzintzun-Camacho³, C. Ceceña-Duran³ and D. Gonzalez-Mendoza^3,*

Phyton-International Journal of Experimental Botany, Vol.88, No.3, pp. 269-275, 2019, DOI:10.32604/phyton.2019.07316

Abstract Phenacoccus solenopsis has been recognized as an aggressively invasive species on cotton plants in different countries. This study was conducted to investigate the effect of green synthesized Cu/Zn-nanoparticles using aqueous leaf extract of Prosopis juliflora (mezquite) against P. solenopsis. The scanning electron microscope (SEM) showed bimetallic nanoparticles of Cu/Zn-NPs with spherical shape with varying size of 74.33 nm to 59.46 nm. More than 30% mortality of P. solenopsis was observed with Cu/Zn-nanoparticles (100 ppm) at 96 hours after treatment. Negligible mortality of P. solenopsis was recorded with Cu/Zn solution (100 ppm) and aqueous P. juliflora extracts. The results of the… More >

Ramzi Bchir^1,2,*, Aslam Sami Djellouli¹, Nadia Zitouna³, Didier Aurelle⁴, Gerard Pergent², Christine Pergent-Martini² and Habib Langar¹

Phyton-International Journal of Experimental Botany, Vol.88, No.2, pp. 171-184, 2019, DOI:10.32604/phyton.2019.05261

Abstract Specimens of Cymodocea (Viridiplantae, Magnoliophyta) collected on the Tunisian coasts showed a particular morphological and anatomical difference with the classical descriptions of Cymodocea nodosa (Ucria) Asch. the only species of this genus reported in the Mediterranean Sea. In order to precise the taxonomic identity of the new specimens we aimed in this work (i) to verify the identity of the new forms, (ii) to evaluate the genetic diversity of the population, (iii) to test the validity of the existing identification keys of the Tunisian Cymodocea populations. Four stations located in two regions of the Tunisian coasts were sampled. Leaf morphological… More >

Xinyue Liu¹, Yunqiao Liu¹, Xiaobo Gong^1,*, Huaxiong Huang²

CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.2, pp. 281-300, 2018, DOI: 10.31614/cmes.2018.04989

Abstract In this work, a three-dimensional axisymmetric model with nanoparticle, receptor-ligand bonds and cell membrane as a system was used to study the quasi-static receptor-mediated endocytosis process of spherical nanoparticles in drug delivery. The minimization of the system energy function was carried out numerically, and the deformations of nanoparticle, receptor-ligand bonds and cell membrane were predicted. Results show that passive endocytosis may fail due to the rupture of receptor-ligand bonds during the wrapping process, and the size and rigidity of nanoparticles affect the total deformation energy and the terminal wrapping stage. Our results suggest that, in addition to the energy requirement,… More >