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    REVIEW

    Drosophila melanogaster as an indispensable model to decipher the mode of action of neurotoxic compounds

    MONALISA MISHRA1,2,*, PUNYATOYA PANDA1, BEDANTA KUMAR BARIK1, AMRITA MONDAL1, MRUTUNJAYA PANDA1

    BIOCELL, Vol.47, No.1, pp. 51-69, 2023, DOI:10.32604/biocell.2022.023392

    Abstract Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in the later stage of life. Those toxic compounds are termed as a neurotoxicant, which can be a physical factor, a toxin, an infection, radiation, or maybe a drug. The incongruities caused due to a neurotoxicant further depend on the toxicity of the compound. More importantly, the neurotoxicity of the compound is associated with the concentration and the time point of exposure. The neurodevelopmental defect appears depending on the toxicity of the compound. A neurodevelopmental defect may be associated with a delay in developmental time, defective… More >

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