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  • Open Access

    REVIEW

    Review of Metaheuristic Optimization Techniques for Enhancing E-Health Applications

    Qun Song1, Chao Gao1, Han Wu1, Zhiheng Rao1, Huafeng Qin1,*, Simon Fong1,2,*

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-49, 2026, DOI:10.32604/cmc.2025.070918 - 09 December 2025

    Abstract Metaheuristic algorithms, renowned for strong global search capabilities, are effective tools for solving complex optimization problems and show substantial potential in e-Health applications. This review provides a systematic overview of recent advancements in metaheuristic algorithms and highlights their applications in e-Health. We selected representative algorithms published between 2019 and 2024, and quantified their influence using an entropy-weighted method based on journal impact factors and citation counts. CThe Harris Hawks Optimizer (HHO) demonstrated the highest early citation impact. The study also examined applications in disease prediction models, clinical decision support, and intelligent health monitoring. Notably, the More >

  • Open Access

    ARTICLE

    A Deep Learning Framework for Heart Disease Prediction with Explainable Artificial Intelligence

    Muhammad Adil1, Nadeem Javaid1,*, Imran Ahmed2, Abrar Ahmed3, Nabil Alrajeh4,*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-20, 2026, DOI:10.32604/cmc.2025.071215 - 10 November 2025

    Abstract Heart disease remains a leading cause of mortality worldwide, emphasizing the urgent need for reliable and interpretable predictive models to support early diagnosis and timely intervention. However, existing Deep Learning (DL) approaches often face several limitations, including inefficient feature extraction, class imbalance, suboptimal classification performance, and limited interpretability, which collectively hinder their deployment in clinical settings. To address these challenges, we propose a novel DL framework for heart disease prediction that integrates a comprehensive preprocessing pipeline with an advanced classification architecture. The preprocessing stage involves label encoding and feature scaling. To address the issue of… More >

  • Open Access

    ARTICLE

    Lightweight YOLOv5 with ShuffleNetV2 for Rice Disease Detection in Edge Computing

    Qingtao Meng, Sang-Hyun Lee*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-15, 2026, DOI:10.32604/cmc.2025.069970 - 10 November 2025

    Abstract This study proposes a lightweight rice disease detection model optimized for edge computing environments. The goal is to enhance the You Only Look Once (YOLO) v5 architecture to achieve a balance between real-time diagnostic performance and computational efficiency. To this end, a total of 3234 high-resolution images (2400 × 1080) were collected from three major rice diseases Rice Blast, Bacterial Blight, and Brown Spot—frequently found in actual rice cultivation fields. These images served as the training dataset. The proposed YOLOv5-V2 model removes the Focus layer from the original YOLOv5s and integrates ShuffleNet V2 into the… More >

  • Open Access

    ARTICLE

    A Convolutional Neural Network-Based Deep Support Vector Machine for Parkinson’s Disease Detection with Small-Scale and Imbalanced Datasets

    Kwok Tai Chui1,*, Varsha Arya1, Brij B. Gupta2,3,4,*, Miguel Torres-Ruiz5, Razaz Waheeb Attar6

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-23, 2026, DOI:10.32604/cmc.2025.068842 - 10 November 2025

    Abstract Parkinson’s disease (PD) is a debilitating neurological disorder affecting over 10 million people worldwide. PD classification models using voice signals as input are common in the literature. It is believed that using deep learning algorithms further enhances performance; nevertheless, it is challenging due to the nature of small-scale and imbalanced PD datasets. This paper proposed a convolutional neural network-based deep support vector machine (CNN-DSVM) to automate the feature extraction process using CNN and extend the conventional SVM to a DSVM for better classification performance in small-scale PD datasets. A customized kernel function reduces the impact… More >

  • Open Access

    ARTICLE

    A Hybrid Deep Learning Multi-Class Classification Model for Alzheimer’s Disease Using Enhanced MRI Images

    Ghadah Naif Alwakid*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-25, 2026, DOI:10.32604/cmc.2025.068666 - 10 November 2025

    Abstract Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that significantly affects cognitive function, making early and accurate diagnosis essential. Traditional Deep Learning (DL)-based approaches often struggle with low-contrast MRI images, class imbalance, and suboptimal feature extraction. This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans. Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization (CLAHE) and Enhanced Super-Resolution Generative Adversarial Networks (ESRGAN). A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient (MCC)-based evaluation method into the design.… More >

  • Open Access

    ARTICLE

    Forecasting Modeling Tool of Crop Diseases across Multiple Scenarios: System Design, Implementation, and Applications

    Mintao Xu1,#, Zichao Jin1,#, Yangyang Tian1, Jingcheng Zhang1,*, Huiqin Ma1, Yujin Jing1, Jiangxing Wu2, Jing Zhai2

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4059-4078, 2025, DOI:10.32604/phyton.2025.074422 - 29 December 2025

    Abstract The frequent outbreaks of crop diseases pose a serious threat to global agricultural production and food security. Data-driven forecasting models have emerged as an effective approach to support early warning and management, yet the lack of user-friendly tools for model development remains a major bottleneck. This study presents the Multi-Scenario Crop Disease Forecasting Modeling System (MSDFS), an open-source platform that enables end-to-end model construction-from multi-source data ingestion and feature engineering to training, evaluation, and deployment-across four representative scenarios: static point-based, static grid-based, dynamic point-based, and dynamic grid-based. Unlike conventional frameworks, MSDFS emphasizes modeling flexibility, allowing… More >

  • Open Access

    ARTICLE

    DenseSwinGNNNet: A Novel Deep Learning Framework for Accurate Turmeric Leaf Disease Classification

    Seerat Singla1, Gunjan Shandilya1, Ayman Altameem2, Ruby Pant3, Ajay Kumar4, Ateeq Ur Rehman5,*, Ahmad Almogren6,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4021-4057, 2025, DOI:10.32604/phyton.2025.073354 - 29 December 2025

    Abstract Turmeric Leaf diseases pose a major threat to turmeric cultivation, causing significant yield loss and economic impact. Early and accurate identification of these diseases is essential for effective crop management and timely intervention. This study proposes DenseSwinGNNNet, a hybrid deep learning framework that integrates DenseNet-121, the Swin Transformer, and a Graph Neural Network (GNN) to enhance the classification of turmeric leaf conditions. DenseNet121 extracts discriminative low-level features, the Swin Transformer captures long-range contextual relationships through hierarchical self-attention, and the GNN models inter-feature dependencies to refine the final representation. A total of 4361 images from the… More >

  • Open Access

    ARTICLE

    Identifying the Causative Pathogen of Rosa roxburghii Tratt. Fruit Rot and Laboratory Screening for Control Agents

    Di Wu1, Chunguang Ren1, Liangliang Li1, Chongpei Zheng2, Wenwen Su1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4079-4090, 2025, DOI:10.32604/phyton.2025.072856 - 29 December 2025

    Abstract To identify the pathogen responsible for fruit rot disease in Rosa roxburghii Tratt. from Guiding County, Guizhou Province, China, diseased fruit samples were collected. The pathogen was isolated, purified, and identified through morphological, molecular, and pathogenic analyses. Subsequently, its biological characteristics were evaluated. Furthermore, to determine the agent with the strongest toxicity against the identified pathogen, the antifungal activity of six chemical and biological agents was evaluated through indoor toxicity assays. Finally, Neopestalotiopsis clavispora was identified as the pathogen responsible for fruit rot disease in R. roxburghii Tratt. The diameter of the pathogen grown under different carbon and… More >

  • Open Access

    COMMUNICATION

    Gastrointestinal resection is associated with urolithiasis severity among inflammatory bowel disease patients

    Vinay Durbhakula1,*, Ziv Savin1, Einat Savin-Shalom2, Stephanie L. Gold2, Kavita Gupta1, Eve Frangopoulos1, Blair Gallante1, William M. Atallah1, Mantu Gupta1

    Canadian Journal of Urology, Vol.32, No.6, pp. 659-668, 2025, DOI:10.32604/cju.2025.067614 - 30 December 2025

    Abstract Background: A well-established correlation exists between Inflammatory Bowel Disease (IBD) and urolithiasis. However, the influence of surgical history on the severity of urolithiasis in IBD patients remains underexplored. This study aims to investigate the association between gastrointestinal (GI) bowel resection and urolithiasis severity in patients with IBD. Methods: This retrospective cohort study analyzed 42 patients diagnosed with both IBD and urolithiasis between 2016 and 2024. Patients were categorized based on their history of bowel resection. Primary outcomes included maximal stone burden, need for urolithiasis surgery, and stone recurrence. Secondary outcomes were stone-related clinical events, multiple… More >

  • Open Access

    ARTICLE

    Low utilization of intracavernosal injection and penile Doppler ultrasound in the evaluation of erectile dysfunction and Peyronie’s disease

    Joon Yau Leong1, Tyler Gaines2, Zachary J. Prebay1, David Ebbott1, Paul H. Chung1,*

    Canadian Journal of Urology, Vol.32, No.6, pp. 589-595, 2025, DOI:10.32604/cju.2025.064125 - 30 December 2025

    Abstract Introduction: Despite the diagnostic value of intracavernosal injections (ICI) and penile Doppler ultrasound (PDUS), there remain barriers to widespread clinical adaptation of these methods. The study aimed to evaluate the practice patterns of utilization of ICI and PDUS in the assessment of erectile dysfunction (ED) and Peyronie’s disease (PD). Methods: Using the TriNetX database (Cambridge, MA, USA), adult (≥18 years) male patients with a diagnosis of ED on oral phosphodiesterase-5 (PDE5) inhibitors were identified. Current Procedural Terminology codes were utilized to identify patients who underwent further evaluation with ICI or PDUS, as well as penile… More >

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