Zehui Zhou¹, Juan Song^2,*, Kelei Guo^1,*

Journal of Psychology in Africa, Vol.35, No.5, pp. 689-694, 2025, DOI:10.32604/jpa.2025.066954 - 24 October 2025

Abstract This study explored the relationship between physical exercise and college students’ mental health, as well as the mediating role of peer relationships and self-esteem. Participants were 1513 undergraduate students (first to fourth year) from six universities in Guangdong Province, China. They completed the Physical Exercise Scale, College Student Mental Health Scale, Peer Relationship Scale, and Self-Esteem Scale. The results following correlation analysis, structural equation modeling, and the bias-corrected percentile bootstrap method indicated. (1) Physical exercise was positively correlated with the mental health of college students and the direct path was significant; (2) Physical exercise and… More >

Madihan Yusof^1,2,3,*, Muhamad Saiful Sulaiman^1,3, Ros Syazmini Mohd Ghani^1,3,4, Sofiyah Mohd Razali^1,5

Journal of Renewable Materials, Vol.13, No.10, pp. 2059-2075, 2025, DOI:10.32604/jrm.2025.02025-0101 - 22 October 2025

Abstract This study investigates the development of an oil palm trunk (OPT) high-performance flame-retardant composite derived from an inexpensive and sustainable biomass source, processed using sodium chloride (NaCl) as a low-cost flame retardant, polyvinyl alcohol (PVA) as an adhesive, and calcium carbonate (CaCO₃) as an additive. The work aims to address the inherent flammability of OPT and to enhance its mechanical performance, dimensional stability, and fire resistance in an environmentally friendly and cost-effective manner. Results indicate that a 10% NaCl treatment optimally improves the performance of the composite, increasing bending strength (MOR) from 5.95 to 12.61 MPa… More > Graphic Abstract

Tian-Tian Li^1,2,3,#, Ming-Yao Meng^1,2,4,#, Zheng Yu⁵, Yang-Fan Guo^1,2,4, Yi-Yi Zhao^1,2,4, Hui Gao^1,2,4, Li-Li Yang^1,2,3, Li-Rong Yang^1,2,3, Meng-Yuan Chu^1,2,3, Shan He^1,2,4, Yuan Liu^1,2,4, Xiao-Dan Wang^1,2,4, Wen-Ju Wang^1,2,4, Zong-Liu Hou^1,2,4, Li-Wei Liao^1,2,4,*, Lin Li^1,2,4,*

Oncology Research, Vol.33, No.11, pp. 3447-3467, 2025, DOI:10.32604/or.2025.065394 - 22 October 2025

Abstract Background: Chimeric antigen receptor T (CAR-T) cell therapies have demonstrated significant clinical efficacy in hematological malignancies. However, their application to solid tumors remains substantially limited by multiple challenges, including the risk of off-target effects. Hence, optimizing CAR-T cells for stronger antigen binding is essential. Methods: In this study, we employed a classical anti-human endothelial growth factor receptor 2 (HER2) single-chain variable fragment (scFv) derived from trastuzumab, alongside an anti-HER2-13 scFv identified from a combinatorial cellular CAR library, for the construction of a third-generation CAR-T cell. Meanwhile, the phenotypes and both in vitro and in vivo functions of… More > Graphic Abstract

Md. Tanvir Raihan¹, Md. Himel Mahmud², Badhon Chandra Mazumder², Md. Nazif Hasan Chowdhury³, Mohammad Tajul Islam^1,*

Journal of Polymer Materials, Vol.42, No.3, pp. 677-711, 2025, DOI:10.32604/jpm.2025.068356 - 30 September 2025

Abstract Electrospinning has gained significant importance across various fields, including biomedicine, filtration, and packaging due to the control it provides over the properties of the resulting materials, such as fiber diameter and membrane thickness. Chitosan is a biopolymer that can be utilized with both natural and synthetic copolymers, owing to its therapeutic potential, biocompatibility, and biodegradability. However, producing electrospun chitosan is challenging due to its high solution viscosity, which often results in the formation of beads instead of uniform fibers. To address this issue, the spinnability of chitosan is significantly enhanced, and the production of continuous More >

Okechukwu J. Obulezi^1,*, Hatem E. Semary², Sadia Nadir³, Chinyere P. Igbokwe⁴, Gabriel O. Orji¹, A. S. Al-Moisheer², Mohammed Elgarhy⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 2991-3027, 2025, DOI:10.32604/cmes.2025.069553 - 30 September 2025

Abstract This study introduces the type-I heavy-tailed Burr XII (TIHTBXII) distribution, a highly flexible and robust statistical model designed to address the limitations of conventional distributions in analyzing data characterized by skewness, heavy tails, and diverse hazard behaviors. We meticulously develop the TIHTBXII’s mathematical foundations, including its probability density function (PDF), cumulative distribution function (CDF), and essential statistical properties, crucial for theoretical understanding and practical application. A comprehensive Monte Carlo simulation evaluates four parameter estimation methods: maximum likelihood (MLE), maximum product spacing (MPS), least squares (LS), and weighted least squares (WLS). The simulation results consistently show… More >

Shengjia Chang, Baojiang Cui^*, Shaocong Feng

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 3805-3827, 2025, DOI:10.32604/cmes.2025.067756 - 30 September 2025

Abstract With the rapid advancement of mobile communication networks, key technologies such as Multi-access Edge Computing (MEC) and Network Function Virtualization (NFV) have enhanced the quality of service for 5G users but have also significantly increased the complexity of network threats. Traditional static defense mechanisms are inadequate for addressing the dynamic and heterogeneous nature of modern attack vectors. To overcome these challenges, this paper presents a novel algorithmic framework, SD-5G, designed for high-precision intrusion detection in 5G environments. SD-5G adopts a three-stage architecture comprising traffic feature extraction, elastic representation, and adaptive classification. Specifically, an enhanced Concrete… More >

Chong Wang^*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.012164

Abstract Please Creating mechanically robust tissue engineering scaffolds capable of delivering growth factors and stem cells in situ for hard tissue repair remains a significant challenge. Inspired by the spiral structure of ice cream, our group developed an advanced 3D printing technique known as cryogenic 3D printing to fabricate polyester-based scaffolds with embedded growth factors. This method utilizes water-in-oil (w/o) polyester emulsions containing growth factors as the printing ink, which is patterned onto a cryogenic substrate. The resulting scaffolds feature a hierarchically porous structure, allowing mesenchymal stem cells (MSCs) to easily attach and proliferate. Additionally, the… More >

Xiaolin Cui¹, Khoon Lim^2,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.1, pp. 1-2, 2025, DOI:10.32604/icces.2025.011173

Abstract 1 Introduction
Joint and cardiovascular diseases, such as osteoarthritis (OA) and myocardial infarction (MI), pose significant clinical challenges due to their limited regenerative capacity. The key to mitigating tissue damage and preventing the progression of OA and MI is to repair or even regenerate the infarcted tissue. At present, cell-based therapy is the primary strategy for tissue repair. Delivered cells could either differentiate into functional cells or secrete paracrine signals to promote onsite cell function. Both mechanisms have demonstrated potential in cartilage and cardiac tissue repair, both preclinically and clinically. In addition to cell therapy,… More >

Liang Yu^1,#, Mingrui Zhao^1,#, Jinhui Liu², Yuqin Yang¹, Lin Zhang², Wenjun Cheng^2,*

Oncology Research, Vol.33, No.10, pp. 3007-3022, 2025, DOI:10.32604/or.2025.065137 - 26 September 2025

Abstract Background: The benefit of adjuvant chemotherapy for stage I ovarian endometrioid carcinoma (OEC) remains controversial. Hence, the study sought to explore its value in stage I OEC patients. Methods: Stage I OEC patients (1988–2018) were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Multivariate Cox analysis was used to control confounders. Logistic regression was used to explore factors associated with adjuvant chemotherapy. Cox regression analysis and Kaplan-Meier curves were used to assess the survival benefits. Single-center clinical data and meta-analysis following PRISMA guidelines provided external validation. Result: Adjuvant chemotherapy correlated with improved survival (Hazard… More >

Elyson De La Cruz^*, Hanh Le, Karthik Meduri, Geeta Sandeep Nadella^*, Hari Gonaygunta

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3569-3582, 2025, DOI:10.32604/cmc.2025.068137 - 23 September 2025

Abstract The rapid integration of artificial intelligence (AI) into software development, driven by large language models (LLMs), is reshaping the role of programmers from traditional coders into strategic collaborators within Industry 4.0 ecosystems. This qualitative study employs a hermeneutic phenomenological approach to explore the lived experiences of Information Technology (IT) professionals as they navigate a dynamic technological landscape marked by intelligent automation, shifting professional identities, and emerging ethical concerns. Findings indicate that developers are actively adapting to AI-augmented environments by engaging in continuous upskilling, prompt engineering, interdisciplinary collaboration, and heightened ethical awareness. However, participants also voiced… More >