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  • Open Access

    ARTICLE

    NT-pro BNP—A marker for worsening respiratory status and mortality in infants and young children with pulmonary hypertension

    Shahnawaz M. Amdani1, Muhammad Umair M. Mian2, Ron L. Thomas3, Robert D. Ross4

    Congenital Heart Disease, Vol.13, No.4, pp. 499-505, 2018, DOI:10.1111/chd.12601

    Abstract Aim: To evaluate predictors of morbidity and mortality in pediatric patients with pulmonary hypertension (PH), laboratory and echocardiographic measures of PH were analyzed.
    Methods: A retrospective review of all infants and children< 2 years of age with PH from January 2011 to August 2016 was conducted. Correlations were determined using Spearman’s rank correlation coefficients. Differences in characteristics between survivors and nonsurvivors were analyzed and Kaplan-Meier survival curves were generated.
    Results: Of 56 patients, the majority were extremely premature; of African American ethnicity; and had bronchopulmonary dysplasia. Patients who died were more likely to have underlying congenital heart disease; have a… More >

  • Open Access

    REVIEW

    Lung development: AT1 and AT2 property

    Yong CHEN1, Yongpin DONG2, Xiaoli DU3,*

    BIOCELL, Vol.44, No.1, pp. 1-5, 2020, DOI:10.32604/biocell.2020.08041

    Abstract The human respiratory system consists of the upper and the lower respiratory tracts. Anatomically, the lower respiratory tract consists of the trachea, bronchi, bronchioles (terminal bronchioles and respiratory bronchioles), alveolar duct, alveolar duct sacs, and alveoli. Alveoli are composed of two epithelial cell types, cuboidal alveolar type 2 (AT2) cells that secrete surfactant to prevent alveolar collapse and function as stem cells to regenerate alveolar type 1 (AT1) cells during damage repair, and squamous AT1 cells that cover most of the surface area of the alveoli and mediate gas exchange. Previous studies mainly focused on AT2 cells; this review summarizes… More >

  • Open Access

    ARTICLE

    A Retrospective Respiratory Gating System Based on Epipolar Consistency Conditions

    Maosen Lian1, Yi Li1, Xiaohui Gu1, Shouhua Luo1,*

    Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 41-48, 2020, DOI:10.32604/mcb.2019.07383

    Abstract Motion artifacts of in vivo imaging, due to rapid respiration rate and respiration displacements of the mice while free-breathing, is a major challenge in micro computed tomography(micro-CT). The respiratory gating is often served for either projective images acquisition or per projection qualification, so as to eliminate the artifacts brought by in vivo motion. In this paper, we propose a novel respiratory gating method, which firstly divides one rotation cycle into a number of segments, and extracts the respiratory signal from the projective image series of current segment by the value of the epipolar consistency conditions (ECC), then in terms of… More >

  • Open Access

    ARTICLE

    Immune strategies of phagoctytic cells stimulated in vitro with live and heat-inactivated Streptococcus pyogenes

    Agustín César MÖHLINGERa, Virginia Paula SIFFREDIa, Serenela CHULIBERTa, Adriana PONESSAb, Rodolfo David NOTARIOb, Diana Graciela DLUGOVITZKYa

    BIOCELL, Vol.37, No.3, pp. 63-69, 2013, DOI:10.32604/biocell.2013.37.063

    Abstract Streptococcus pyogenes (group A Streptococcus) is frequently involved in a wide range of human diseases. Here we evaluated polymorphonuclear neutrophils and mononuclear cells from healthy subjects for their bactericidal function after stimulation with live and inactivated Streptococcus pyogenes (Streptococcus Group A). Mononuclear cells and Neutrophils were isolated from heparinized blood samples (n=18) using a Ficoll-Hypaque gradient and cultured in RPMI 1640 for 18 hours with a suspension of either live or inactivated Streptococcus pyogenes. Both the respiratory burst (flow cytometry) and nitrite, TNF and IL17 production (ELISA) were measured in the cell culture supernatants. An increased respiratory burst (expressed as… More >

  • Open Access

    ARTICLE

    Knockdown of apoptosis-inducing factor disrupts function of respiratory complex

    MIROSLAV VAŘECHA1*, DANIELA PÁCLOVÁ2, JIŘINA PROCHÁZKOVÁ2, PAVEL MATULA1, DUŠAN CMARKO3, AND MICHAL KOZUBEK1

    BIOCELL, Vol.36, No.3, pp. 121-126, 2012, DOI:10.32604/biocell.2012.36.121

    Abstract Recent findings suggest that apoptotic protein apoptosis-inducing factor (AIF) may also play an important non-apoptotic function inside mitochondria. AIF was proposed to be an important component of respiratory chain complex I that is the major producer of superoxide radical. The possible role of AIF is still controversial. Superoxide production could be used as a valuable measure of complex I function, because the majority of superoxide is produced there. Therefore, we employed superoxide-specific mitochondrial fluorescence dye for detection of superoxide production. We studied an impact of AIF knockdown on function of mitochondrial complex I by analyzing superoxide production in selected cell… More >

  • Open Access

    ARTICLE

    Analysis of methodologies for the study of composition and biochemical carbohydrate changes in harvest and postharvest onion bulbs

    Abrameto MA, CM Pozzo Ardizzi, MI Gil, LM Molina

    Phyton-International Journal of Experimental Botany, Vol.79, pp. 123-132, 2010, DOI:10.32604/phyton.2010.79.123

    Abstract Costly investments in storage and transport of onion bulbs makes it increasingly important to identify cultivars with the best chance of long-term storage. This paper discusses our own and other researchers’ results and laboratory procedures on onion’s pungency, soluble solids, dry matter, respiration rate, carbohydrates and catabolism-related enzymes under different storage conditions. The variability in parameters such as carbohydrate composition, pungency, soluble solids and soluble uronic acid concentration in water is growth dependent, and defines the quality of onion bulbs at harvest time. During storage, these parameters can be modified by environmental conditions, presence of pathogens or termination of dormancy.… More >

  • Open Access

    ARTICLE

    Ultrastructural characteristics of the lung of Melanophryniscus stelzneri stelzneri (Weyenberg, 1875) (Anura, Bufonidae)

    GLADYS N. HERMIDA, ALEJANDRO FARÍAS, LUISA E. FIORITO

    BIOCELL, Vol.26, No.3, pp. 347-355, 2002, DOI:10.32604/biocell.2002.26.347

    Abstract The lung of the toad, Melanophryniscus stelzneri stelzneri was studied using scanning and transmission electron microscopy. In M.s.stelzneri the parenchyma forms a polygonal network arrangement, therefore the parenchyma is edicular. These spaces are delimited by the interconnection of third order septa which are covered by respiratory epithelium. Small patches of ciliated epithelium without goblet cells appear irregularly distributed on the septa. The respiratory epithelium consists of one type of pneumocyte, which shows characteristics of both type I and type II alveolar cells of higher vertebrates. The pneumocytes are irregular in shape and possess attenuated cytoplasmic processes, which spread around the… More >

  • Open Access

    ABSTRACT

    Study on fracture behaviors of concrete using electronic speckle pattern interferometry and finite element method

    Helen Hongniao Chen1, Ray Kai Leung Su1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.15, No.3, pp. 91-102, 2010, DOI:10.3970/icces.2010.015.091

    Abstract In this study, Electronic Speckle Pattern Interferometry (ESPI) technique was used to measure the surface displacement and strain fields around cracks in concrete beams. ESPI has high accuracy and can determine full-field deformations of concrete. However, tiny rigid-body movements of beam specimens can spoil the ESPI measurement and cause virtual deformations and false strains. Based on the theory of geometrical optics, this paper proposes a method to eliminate the false strains caused by rigid-body motion. The correction procedure was validated experimentally. Furthermore, the crack evolution in a pre-notched beam is presented. The critical minimum crack width of a microcrack is… More >

  • Open Access

    ABSTRACT

    Establishment of the Realistic Breathing Patterns in Different Exercise Conditions by Experimental Measurement

    chun-chi Li1, chin-chiang Wang2, yin-chia Su2, yu-chen Chu2, chia-chu Weng2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.11, No.2, pp. 31-32, 2009, DOI:10.3970/icces.2009.011.031

    Abstract The aim of this paper was to establish the realistic breathing patterns in different exercise conditions by experimental measurement. Generally, the human inhalation rate varies from 15 L/min at rest to 135 L/min for intense exercise and the breathing cycles are varied with different exercise conditions. Previous author have used symmetric Weibel configuration to establish three realistic breathing patterns, i. e., resting (inhalation rate, 15 L/min), light activity (inhalation rate, 30 L/min), and moderate exercise (inhalation rate, 60 L/min). In this study, in addition to reconstructing the three realistic breathing patterns of above mention, we expand the establishment of the… More >

  • Open Access

    ARTICLE

    Evaluation of Biodegradation in Aqueous Medium of Poly(Hydroxybutyrate-Co-Hydroxyvalerate)/Carbon Nanotubes Films in Respirometric System

    Larissa Stieven Montagna, Isabela CÉSAR Oyama, Rita de CÁSSIA Barbosa Camargo Lamparelli, Ana Paula Silva, THAÍS Larissa do Amaral Montanheiro, Ana Paula Lemes*

    Journal of Renewable Materials, Vol.7, No.2, pp. 117-128, 2019, DOI:10.32604/jrm.2019.00036

    Abstract Biodegradable polymers have been increasingly used for scientific and commercial applications because they are similar to some conventional thermoplastics and exhibit the ability of self-degradation. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanocomposites films with 1 and 2 wt% of carbon nanotubes (CNT) were prepared by solution mixing, followed by solvent evaporation. In this work, PHBV/CNT nanocomposites were submitted to biodegradation in an aqueous medium for 34 days through a respirometric system. Then, the PHBV films were analyzed by the CO2 production and mineralization as a response of a microbial attack, which was monitored by back titration during all the experiment. The films were also… More >

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