SEUNGIL KIM, GUN-DONG KIM^*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.073781 - 23 January 2026

Abstract Neutrophil extracellular trap (NET) formation or NETosis is a specialized innate immune process in which neutrophils release chromatin fibers decorated with histones and antimicrobial proteins. Although pivotal for pathogen clearance, aberrant NETosis has emerged as a critical modulator of acute and chronic respiratory pathologies, including acute respiratory distress syndrome, asthma, and chronic obstructive pulmonary disease. Dysregulated NET release exacerbates airway inflammation by inducing epithelial injury, mucus hypersecretion, and the recruitment of inflammatory leukocytes, thereby accelerating tissue remodeling and functional decline. Mechanistically, NETosis is governed by peptidyl arginine deiminase 4 (PADI4)-mediated histone citrullination, NADPH oxidase-dependent reactive More >

Jordan L. Mendelson^1,*, Jordan Kassab¹, Phillip Westbrook¹, Katie Yang², Anthony Corcoran¹

Canadian Journal of Urology, Vol.32, No.6, pp. 673-676, 2025, DOI:10.32604/cju.2025.063770 - 30 December 2025

Abstract Stereotactic body radiotherapy (SBRT) for prostate cancer is a generally well-tolerated treatment but can rarely lead to complications such as fistula formation. We report a 69-year-old male on maintenance ibrutinib for chronic lymphocytic leukemia who developed a fistula between his bladder and vas deferens in the setting of ascending scrotal infection. Despite his prior history of SBRT, the fistula was successfully treated with minimally invasive measures. A combination of abscess debridement, urinary diversion, and broad-spectrum antibiotics helped to achieve fistula resolution. The unique presentation described herein highlights the importance of early aggressive intervention for source More >

Norbert Nass^1,2,#, Mohamad-Kamal Yaakoub^1,#, Alexandra-Victorita Simion³, Hartmut Kroll⁴, Sabine Westphal³, Judith Pannier¹, Gerhard Behre^1,*

Oncology Research, Vol.33, No.10, pp. 2923-2935, 2025, DOI:10.32604/or.2025.067561 - 26 September 2025

Abstract Background: Patients with hemato-oncological malignancies may respond insufficiently to vaccination, especially in terms of antibody titer. The antibody response depends on the type of malignancy as well as the type and timing of treatment. We intended to evaluate this using real-world data from patients of our regional hospital. This study also considers the role of immune status, including T-cell activation markers, in predicting vaccination success. Methods: Seventeen patients of our hospital having a hematological malignancy were included in this study, including myeloma, lymphoma, as well as acute myeloid leukemia (AML) and chronic lymphoid leukemia (CLL).… More >

Won-Yang Cho, Sangjun Lee^*

CMC-Computers, Materials & Continua, Vol.84, No.2, pp. 2847-2863, 2025, DOI:10.32604/cmc.2025.066373 - 03 July 2025

Abstract The classification of respiratory sounds is crucial in diagnosing and monitoring respiratory diseases. However, auscultation is highly subjective, making it challenging to analyze respiratory sounds accurately. Although deep learning has been increasingly applied to this task, most existing approaches have primarily relied on supervised learning. Since supervised learning requires large amounts of labeled data, recent studies have explored self-supervised and semi-supervised methods to overcome this limitation. However, these approaches have largely assumed a closed-set setting, where the classes present in the unlabeled data are considered identical to those in the labeled data. In contrast, this… More >

Idongesit Sunday Ambrose¹, Sunday Edet Etuk², Okechukwu Ebuka Agbasi^3,*, Ijah Ioryue Silas⁴, Unyime Udoette Saturday⁵, Eyo Edet Orok⁶

Revue Internationale de Géomatique, Vol.34, pp. 335-350, 2025, DOI:10.32604/rig.2025.064552 - 13 June 2025

Abstract Road construction and traffic congestion are increasingly recognized as major contributors to environmental and public health challenges in urban Nigeria, particularly in Rivers State. Despite growing urbanization, a gap remains in localized data on the combined effects of air and noise pollution in hydrocarbon-polluted environments. This study addresses that gap by conducting a preliminary environmental health assessment focused on the Port Harcourt Ring Road project. Air quality and noise levels were monitored in situ at 20 strategically selected locations, with five control points included for baseline comparison. Digital portable meters were used to measure concentrations of… More >

Kuo-Yang Huang¹, Sheng-Chien Lin^2,3, Chun-Hung Su^4,5,6, Sheng-Wen Wu^4,7, Ching-Chi Tseng^8,9, Wei-Chin Hung¹⁰, Shih-Pin Chen^4,5, Yu-Hsiang Kuan^2,3,*

BIOCELL, Vol.49, No.2, pp. 315-334, 2025, DOI:10.32604/biocell.2025.061073 - 28 February 2025

Abstract ABSTRACT: Background: Acute respiratory distress syndrome (ARDS) is the major therapeutic dilemma associated with significant inflammation and severe pulmonary dysfunction. Liriodendrin is a bioactive compound extract from traditional Chinese medicine, historically utilized for modulating inflammatory responses and alleviating symptoms in multiple disease models. Methods: At present, BALB/c mice were used to explore the effects of liriodendrin on lipopolysaccharide (LPS)-induced ARDS. Before LPS was administered, the mice were treated with either liriodendrin or dexamethasone. Leukocyte infiltration, lung edema, and alveolar-capillary barrier integrity were evaluated in the bronchoalveolar lavage fluid (BALF) and pulmonary parenchyma. The expression of adhesion… More >

Jianfeng He^1,2, Haowei Ye¹, Jie Ning¹, Hui Zhou^1,2,*, Bo She^3,*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3355-3372, 2024, DOI:10.32604/cmc.2024.048706 - 15 May 2024

Abstract In addressing the challenge of motion artifacts in Positron Emission Tomography (PET) lung scans, our study introduces the Triple Equivariant Motion Transformer (TEMT), an innovative, unsupervised, deep-learning-based framework for efficient respiratory motion correction in PET imaging. Unlike traditional techniques, which segment PET data into bins throughout a respiratory cycle and often face issues such as inefficiency and overemphasis on certain artifacts, TEMT employs Convolutional Neural Networks (CNNs) for effective feature extraction and motion decomposition.TEMT’s unique approach involves transforming motion sequences into Lie group domains to highlight fundamental motion patterns, coupled with employing competitive weighting for More >

XUNAN ZHAO^#, EMMANUEL MAGO^#, DAN WENG^*

BIOCELL, Vol.47, No.10, pp. 2151-2162, 2023, DOI:10.32604/biocell.2023.030570 - 08 November 2023

Abstract Acute respiratory distress syndrome (ARDS) is a life-threatening pulmonary disease typically caused by microbial infections, trauma, inhalation of harmful gases, and other factors. It is characterized by an inflammation in the lungs and increased alveolar permeability, leading to pulmonary edema and consequently, a low oxygen supply or hypoxemia. ARDS is responsible for 1 in 10 admissions to intensive care units, and the mortality rate for patients with severe ARDS is as high as 46%. Extensive efforts have been devoted to investigating the pathological mechanisms of ARDS to develop new effective clinical strategies. Recent studies have More > Graphic Abstract

Valarmathi Ramasamy^1,*, Dhandapani Samiappan², R. Ramesh³

Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 1365-1380, 2023, DOI:10.32604/iasc.2023.032155 - 05 January 2023

Abstract Owing to the recent trends in remote health monitoring, real-time applications for measuring Heartbeat Rate and Respiration Rate (HARR) from video signals are growing rapidly. Photo Plethysmo Graphy (PPG) is a method that is operated by estimating the infinitesimal change in color of the human face, rigid motion of facial skin and head parts, etc. Ballisto Cardiography (BCG) is a nonsurgical tool for obtaining a graphical depiction of the human body’s heartbeat by inducing repetitive movements found in the heart pulses. The resilience against motion artifacts induced by luminance fluctuation and the patient’s mobility variation… More >

Juan Liu^1,2,*, Meiqun Zheng¹, Xueshuang Chen¹

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 271-283, 2023, DOI:10.32604/phyton.2022.023397 - 06 September 2022

Abstract Chinese hickory (Carya cathayensis Sarg.) is a popular nut tree in China, but there is little information about the influences of fertilization on soil CO₂ efflux and soil microbial biomass. This study evaluated the short-term effects of different fertilizer applications on soil CO₂ efflux and soil microbial biomass in Chinese hickory stands. Four fertilizer treatments were established: control (CK, no fertilizer), inorganic fertilizer (IF), organic fertilizer (OF), and equal parts organic and inorganic N fertilizers (OIF). A field experiment was conducted to measure soil CO₂ effluxes using closed chamber and gas chromatography techniques. Regardless of the fertilization practices,… More >