Shalu¹, Twinkle Acharya¹, Dhwanilnath Gharekhan^1,*, Dipak Samal²

Revue Internationale de Géomatique, Vol.33, pp. 111-134, 2024, DOI:10.32604/rig.2024.051788

Abstract Seismic vulnerability modeling plays a crucial role in seismic risk assessment, aiding decision-makers in pinpointing areas and structures most prone to earthquake damage. While machine learning (ML) algorithms and Geographic Information Systems (GIS) have emerged as promising tools for seismic vulnerability modeling, there remains a notable gap in comprehensive geospatial studies focused on India. Previous studies in seismic vulnerability modeling have primarily focused on specific regions or countries, often overlooking the unique challenges and characteristics of India. In this study, we introduce a novel approach to seismic vulnerability modeling, leveraging ML and GIS to address these gaps. Employing Artificial Neural… More >

Wai Tuck Chow^*, Jia Tai Lau

Digital Engineering and Digital Twin, Vol.2, pp. 103-130, 2024, DOI:10.32604/dedt.2024.044545

Abstract This paper presents a novel approach to using supervised learning with a shallow neural network to increase the efficiency of the finite element analysis of holes under biaxial load. With this approach, the number of elements in the finite element analysis can be reduced while maintaining good accuracy. The neural network will be used to predict the maximum stress for holes of different configurations such as holes in a finite-width plate (2D), multiple holes (2D), staggered holes (2D), and holes in an infinite plate (3D). The predictions are based on their respective coarse mesh with only 2 elements along the… More >

CHENG-GONG LUO^1,2,#, JIAO ZHANG^1,#, YUN-ZHAO AN¹, XUAN LIU¹, SHUAI-JIE LI¹, WEI ZHANG¹, KAI LI¹, XU ZHAO¹, DONG-BO YUAN¹, LING-YUE AN¹, WEI CHEN², YE TIAN^1,*, BIN XU^1,*

BIOCELL, Vol.48, No.5, pp. 771-792, 2024, DOI:10.32604/biocell.2024.048878

Abstract Background: Ferroptosis, a lipid peroxidation-mediated programmed cell death, is closely linked to tumor development, including prostate cancer (PCa). Despite established connections between ferroptosis and PCa, a comprehensive investigation is essential for understanding its impact on patient prognosis. Methods: A risk model incorporating four ferroptosis-related genes was developed and validated. Elevated risk scores correlated with an increased likelihood of biochemical recurrence (BCR), diminished immune infiltration, and adverse clinicopathological characteristics. To corroborate these results, we performed validation analyses utilizing datasets from both the Cancer Genome Atlas Cohort (TCGA) and the Gene Expression Synthesis Cohort (GEO). Moreover, we conducted further investigations into the… More >

YUANYUAN LI¹, BITAO ZHANG¹, ZILONG CUI¹, PEIJIAN FAN¹, SHAOXIAN WANG^1,2,*

BIOCELL, Vol.48, No.5, pp. 731-744, 2024, DOI:10.32604/biocell.2024.048820

Abstract Background: Depression is becoming increasingly prevalent around the world, imposing a substantial burden on individuals, families, as well as society. Quercetin is known to be highly effective in treating depression. However, additional research is needed to dissect the mechanisms of its anti-depressive effects. Methods: For this study, Sprague-Dawley (SD) rats were randomized into the control, model, quercetin, or fluoxetine group. The latter three groups were exposed to chronic unpredictable mild stress (CUMS) for 42 d. The first two groups received saline solution daily via oral gavage. Meanwhile, the quercetin group was orally administered a quercetin suspension (52.08 mg/kg) every day,… More >

XINRU FENG¹, LI XIAO^2,*

BIOCELL, Vol.48, No.5, pp. 793-801, 2024, DOI:10.32604/biocell.2024.048395

Abstract Background: Galectin 2 (LGALS2) is a protein previously reported to serve as a mediator of disease progression in a range of cancers. The function of LGALS2 in oral squamous cell carcinoma (OSCC), however, has yet to be explored, prompting the present study to address this literature gap. Methods: Overall, 144 paired malignant tumor tissues and paracancerous OSCC patient samples were harvested and the LGALS2 expression levels were examined through qPCR and western immunoblotting. The LGALS2 coding sequence was introduced into the pcDNA3.0 vector, to enable the overexpression of this gene, while an LGALS2-specific shRNA and corresponding controls were also obtained.… More >

JING HUI^1,2, NANA SUN³, YONG LIU⁴, CHUNBO YU^1,2, YONG KE⁴, YONG CAO⁴, ANXIAO YU⁴, QINGHONG KONG^1,2,*, YUN LIU^1,2,4,*

BIOCELL, Vol.48, No.5, pp. 803-815, 2024, DOI:10.32604/biocell.2024.047122

Abstract Background: Although it has been established that the human Solute Carrier Family 22 (SLC22) functions as a cationic transporter, influencing cellular biological metabolism by modulating the uptake of various cations, its impact on cancer prognosis remains unclear. Methods: We conducted a comprehensive analysis utilizing data from The Cancer Genome Atlas (TCGA) and other databases to assess the prognostic value and functional implications across various tumors. Silence of SLC22A1 RNA in glioma U251 cells was performed to access the impact of SLC22A1 on lower-grade glioma (LGG) progression. Results: Our findings demonstrated a significant correlation between SLC22A1 expression and the survival time… More >

Sowon Lee¹, Boyoung Kim^1,*, Chung Kil Park^2,*

International Journal of Mental Health Promotion, Vol.26, No.4, pp. 251-260, 2024, DOI:10.32604/ijmhp.2024.048803

Abstract This study explored how mental health professionals collaborate with peer supporters with mental disabilities in a community mental health institution. From January 19 to February 23, 2021, three 60 min interviews were conducted with six mental health professionals working at a Korean community center. The results were qualitatively analyzed and divided into four themes and eight categories. The four themes were the perceptions of and challenges in working with peer supporters with mental disabilities, conflict and confusion about working with peer supporters, forming partnerships with peer supporters, and policy support for peer supporters’ job security. Participants reported vague anxiety about… More >

Yulei Chen¹, Zhaojun Chen^1,2, Shichao Wang¹, Yang Hang¹, Jianpeng Guo^1,*

International Journal of Mental Health Promotion, Vol.26, No.4, pp. 303-315, 2024, DOI:10.32604/ijmhp.2024.046863

Abstract Social-Emotional Competency (SEC), regarded as a critical psychological resource for individuals to adapt to social environments, is an effective protective factor for students’ mental health, impacting their future success and well-being. Analyzing the impact of SEC on university students’ mental health can offer valuable insights for nurturing talents with healthy psychological and physical development. Based on data from two large-scale surveys of Chinese university students, this study designed two comprehensive Multiple Mediation Models involving SEC, stress, coping strategies, and stress reaction to explore the pathway of emotion nurturing mentality. Study 1 utilized a parallel mediation model to examine the relationships… More >

Yanjing Cao¹, Chenchen Xu^1,2, Qi Li¹, Shan Lu^1,2,*, Jing Xiao^1,*

International Journal of Mental Health Promotion, Vol.26, No.4, pp. 261-269, 2024, DOI:10.32604/ijmhp.2024.043729

Abstract Background: Valid and reliable measures of depressive symptoms are crucial for understanding risk factors, outcomes, and interventions across rural and urban settings. Despite this need, the longitudinal invariance of these measures over time remains understudied. This research explores the structural components of the Center for Epidemiological Studies Depression Scale (CES-D) and examines its consistency across various living environments and temporal stability in a cohort of Chinese teenagers. Method: In the initial phase, 1,042 adolescents furnished demographic details and undertook the CES-D assessment. After a three-month interval, 967 of these participants repeated the CES-D evaluation. The study employed Confirmatory factor analysis… More >

Qi Lu^1,2, Longfei Jin², Cuiling Tong³, Feng Liu², Bei Huang², Dejian Zhang^1,2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 661-679, 2024, DOI:10.32604/phyton.2024.049733

Abstract A Plant Biostimulant is any substance or microorganism applied to plants to enhance nutrition efficiency, abiotic stress tolerance, and/or crop quality traits, regardless of its nutrient content. The application of Plant biostimulants (PBs) in production can reduce the application of traditional pesticides and chemical fertilizers and improve the quality and yield of crops, which is conducive to the sustainable development of agriculture. An in-depth understanding of the mechanism and effect of various PBs is very important for how to apply PBs reasonably and effectively in the practice of crop production. This paper summarizes the main classification of PBs; The growth… More >