XIANGCAI YANG1,2,*, YA XU3, SHUTING MEI1, JIEJING LI3,*
BIOCELL, Vol.46, No.2, pp. 463-470, 2022, DOI:10.32604/biocell.2021.014834
Abstract Cell migration is a finely tuned biological process that often involves epithelial-mesenchymal transition (EMT).
EMT is typically characterized by the upregulation of mesenchymal markers such as Snail1. This process has been shown
to be of critical importance to normal developmental processes, including neural crest migration and invasion.
Interestingly, similar mechanisms are utilized in disease processes, such as tumor metastasis and migration. Notably,
EMT and EMT-like processes confer tumor cells with the ability to migrate, invade, and adopt stem cell-like
properties that largely account for immunosuppression and tumor recurrence. Therefore, identifying sensitive EMT
markers may contribute to cancer prognosis and diagnosis… More >
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