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    ARTICLE

    Data-independent acquisition mass spectrometry quantitative proteomic analysis reveals that skin aging-related proteins differ between men and women

    HUI ZHANG1,3,#, SHIRUI CHEN1,3,#, MENGTING LIU1,2, YAOCHI WANG1,2, CONG XIN1,2, JING MA1,3, XIAODONG ZHENG1,2, YUANDI HUANG1,2, BO ZHANG3,4, XUEJUN ZHANG1,2, LIANGDAN SUN1,2,*, SEN YANG1,3,*

    BIOCELL, Vol.45, No.5, pp. 1321-1335, 2021, DOI:10.32604/biocell.2021.016524

    Abstract The skin is the largest organ of the human body, and its aging is visible to the naked eye. The aging rate of men and women is slightly different. This study compared the protein expression of skin samples on the curved forearms of 11 healthy women and 9 healthy men. Quantitative proteomics analysis found that the expression of epidermal proteins in men and women of the same age group was different. Compared with female skin, in male skin, 20 proteins were upregulated, and 7 proteins were downregulated. These data suggest that men and women have differences in the speed of… More >

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