Olga S. Tsiftsoglou^1,*, Vladimir Mihailovic², Nikola Sreckovic², Jelena S. Katanic Stankovic³, Kyriakos Michail Dimitriadis¹, Michalis K. Stefanakis⁴, Diamanto Lazari¹

Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.075566 - 30 January 2026

Abstract Achillea species are known for their healing properties since ancient times. There is extensive literature on their pharmacological action due to their bioactive compounds. The present study aimed to investigate the antioxidant and antimicrobial effects of hydroalcoholic extracts from the inflorescences and leaves of the species Achillea crithmifolia Waldst. and Kit., A. grandifolia Friv. and A. millefolium L. The phytochemical profiles of all extracts were evaluated both by NMR spectroscopy and LC-MS analysis, and the results were consistent with the spectrophotometrically determined total phenolic (TP: 125.42–191.98 mg/g) and total flavonoid (TF: 47.34–180.02 mg/g) contents. All the extracts were tested More >

Mario D’Ambrosio¹, Elisabetta Bigagli^1,*, Lorenzo Cinci¹, Cecilia Brunetti^2,*, Edgardo Giordani³, Francesco Ferrini³, Cristina Luceri¹

Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.073250 - 30 January 2026

Abstract Moringa oleifera (MO) is traditionally used to mitigate inflammatory-mediated disorders; however, the influence of ecotypic variation on its anti-inflammatory activity remains poorly understood. In this study, we compared the phytochemical composition and anti-inflammatory activity of ethanolic extracts obtained from fresh and dried leaves of four MO ecotypes (India, Paraguay, Mozambique, and Pakistan), all grown under the same outdoor conditions, as well as two commercial powders (Just Moringa and WISSA), using LPS-stimulated RAW 264.7 macrophages. Extracts from fresh leaves were 19–43% more cytotoxic than those from dried leaves, depending on the ecotype, likely due to higher cyanogenic… More >

Oleh Koshovyi¹, Amal D. Premarathna², Rando Tuvikene², Valdas Jakštas^3,4, Vaidotas Žvikas³, Yurii Hrytsyk⁵, Lyubov Grytsyk⁵, Andriy Grytsyk⁵, Jaan Liira⁶, Ain Raal^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3991-4019, 2025, DOI:10.32604/phyton.2025.074153 - 29 December 2025

Abstract Gilia capitata Sims (Polemoniaceae) is an annual herbaceous plant widely distributed in western North America and cultivated as an ornamental flower. The detailed chemical composition and pharmacological properties of this plant have not been previously reported. This study aimed to investigate the chemical composition and pharmacological activity of aqueous-ethanolic extracts derived from different plant parts (herb, flowers, stems, roots, and fruits). HPLC analysis identified 12 phenolic compounds and 16 amino acids in the aqueous-ethanolic extracts obtained from these plant parts. The biological effects of the extracts were evaluated in vitro, including cytotoxicity, anti-inflammatory response, and wound-healing potential.… More >

Fang Liao, Xiurong Wang^*, Muyan Xie, Lixin Duan

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3667-3686, 2025, DOI:10.32604/phyton.2025.069653 - 01 December 2025

Abstract Bryophytes play important ecological roles in terrestrial ecosystems, but their growth is often influenced by environmental factors and chemical interactions with surrounding vegetation. Fallen leaves are an important source of allelopathic substances, yet little is known about their impact on mosses. This study investigates the allelopathic effects of fallen leaves from Cinnamomum camphora, Pinus massoniana, and Bambusa emeiensis on the bryophyte Thuidium kanedae in Guiyang. The litter aqueous extract (0.0125 g/mL (T1), 0.025 g/mL (T2), 0.05 g/mL (T3), 0.1 g/mL (T4) and distilled water control (CK)) was used to regularly water and culture T. kanedae. During the 120-day test period,… More >

Sy-Yu Shiau^*, Shuting Ni, Yanli Yu, Songling Cai, Wenbo Huang

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3047-3060, 2025, DOI:10.32604/phyton.2025.070289 - 29 October 2025

Abstract Consumers are increasingly demanding natural colorants that are safe and offer health benefits. In addition to their ornamental characteristics, Kanzan cherry (KC) blossoms present a promising source of red-hued natural colorants and functional bioactive substances. This research utilized distilled water to extract KC petals (KCP) and their ground powders (KCPP) under varying temperatures (30°C–90°C) and times (30–180 min). The total monomeric anthocyanins (TMAC) and total phenolics (TPC) in the extracts were evaluated via the pH differential and Folin–Ciocalteu methods. Antioxidant capacities were assessed by DPPH free radical scavenging ability and reducing power. Results indicated that… More >

Anjali Kariyarath Valappil^1,#, Reshmi Akter^2,#, Muhammad Awais², Dong Uk Yang³, Daehyo Jung², Li Ling⁴, Eun Kim⁵, Kyu Hyeong Yoon⁵, Yoon Ok Lee⁵, Deok Chun Yang^1,2,4,*

BIOCELL, Vol.49, No.9, pp. 1771-1795, 2025, DOI:10.32604/biocell.2025.069145 - 25 September 2025

Abstract Objectives: The phytochemical investigation of traditional herbal medicines holds significant promise for modern drug discovery, particularly in cancer therapy. This study aimed to evaluate the cytotoxicity, apoptosis induction, and immune-modulatory activities of extracts from three herbal medicines with historical use in traditional medicine—Acanthopanax sessiliflorus, Phragmites communis, and Pinus densiflora, as well as their combined extract (GMAS 01/COM), on human lung cancer cells (A549) and normal cell lines, including murine macrophages (RAW 264.7) and human keratinocytes (HaCaT). Methods: Plant extracts were prepared using aqueous extraction, sonication, and rotary evaporation. The total phenolic and flavonoid contents were quantified using the… More >

Deen Bandhu Dimri¹, Manisha Nigam^1,*, Naresh Singh¹, Shilpa Semwal¹, Marcello Iriti^2,3,*, Abhay Prakash Mishra⁴

Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 1007-1027, 2025, DOI:10.32604/phyton.2025.061270 - 31 March 2025

Abstract Cornus capitata, commonly known as the Himalayan strawberry, is a dogwood species from the family Cornaceae. Dogwood plants have been used extensively to practice conventional medicine due to their biological activities; however, the mechanisms behind these activities, particularly in C. capitata, remain largely unexplored. This study focuses on the preliminary phytochemical screening, antioxidant activity, anti-diabetic potential, and antimicrobial profiling of different extracts (i.e., leaves, bark, and fruit) from C. capitata to evaluate its potential pharmaceutical and medicinal applications. The in-vitro antioxidant activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay, Ferric-reducing antioxidant power (FRAP) assay, and Superoxide Anion Scavenging assay.… More > Graphic Abstract

Emma Kieny^1,2,3, Kévin Candelier^2,3,*, Louis Milhe¹, Yannick Estevez⁴, Cyrielle Sophie⁴, Romain Lehnebach¹, Jérémie Damay^2,3, Daniela Florez¹, Emeline Houël⁵, Marie-France Thévenon^2,3, Julie Bossu⁴

Journal of Renewable Materials, Vol.13, No.1, pp. 79-100, 2025, DOI:10.32604/jrm.2024.056731 - 20 January 2025

Abstract The valorization of Amazonian wood residues into active chemical compounds could be an eco-friendly, cost-effective and valuable way to develop wood preservative formulations to enhance the decay and termite resistance of low-durable wood species. Wacapou (Vouacapoua americana., Fabaceae) is a well-known Guianese wood species commonly used in local wood construction due to its outstanding natural durability, which results from the presence of a large panel of extractives compounds. In addition, its industrial processing generates large amounts of residues. Wacapou residues were extracted by maceration using four different solvents (water/ethanol, ethyl acetate, hexane and dichloromethane/methanol), separately and… More > Graphic Abstract

Mingzhao Han¹, Susilawati Kasim^1,*, Zhongming Yang², Xi Deng², Noor Baity Saidi³, Md Kamal Uddin¹, Effyanti Mohd Shuib¹

Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2149-2166, 2024, DOI:10.32604/phyton.2024.054009 - 30 September 2024

Abstract It is imperative to enhance crop yield to meet the demands of a burgeoning global population while simultaneously safeguarding the environment from adverse impacts, which is one of the dominant challenges confronting humanity in this phase of global climate change. To overcome this problem and reduce dependency on chemical fertilizer, scientists now view the implementation of biostimulant strategies as a cost-effective and environmentally friendly approach to achieving sustainable agriculture. Plant extracts are rich in bioactive phytocompounds, which can enhance plant resistance to disease, pest, and abiotic stresses (e.g., drought, salinity, and extreme temperature), and promote… More >

Liliane Nga¹, Benoit Ndiwe^1,2, Achille Bernard Biwolé¹, Antonio Pizzi^3,*, Jean Jalin Eyinga Biwole¹, Joseph Zobo Mfomo¹

Journal of Renewable Materials, Vol.12, No.3, pp. 553-568, 2024, DOI:10.32604/jrm.2023.046568 - 11 April 2024

Abstract Extracts of plant origin, particularly tannins, are attracting growing interest for the sustainable development of materials in the industrial sector. The discovery of new tannins is therefore necessary. The aim of this work was to contribute to the understanding of the properties of Paraberlinia bifoliolata tannin by Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectroscopy MALDI-TOF/MS and Carbon 13 Nuclear Magnetic Resonance (¹³C NMR). The chemical composition of tannin extracted from Paraberlinia bifoliolata bark was determined, as was the mechanical strength of the resin hardened with Acacia nilotica extracts. Yield by successive water extraction was 35%. MALDI-TOF/MS… More >