Chun Yang1, Dalin Tang2, Chun Yuan3, Thomas S. Hatsukami4, Jie Zheng5, Pamela K. Woodard5
CMES-Computer Modeling in Engineering & Sciences, Vol.19, No.3, pp. 233-246, 2007, DOI:10.3970/cmes.2007.019.233
Abstract It has been recognized that fluid-structure interactions (FSI) play an important role in cardiovascular disease initiation and development. However, in vivo MRI multi-component FSI models for human carotid atherosclerotic plaques with bifurcation and quantitative comparisons of FSI models with fluid-only or structure-only models are currently lacking in the literature. A 3D non-Newtonian multi-component FSI model based on in vivo/ex vivo MRI images for human atherosclerotic plaques was introduced to investigate flow and plaque stress/strain behaviors which may be related to plaque progression and rupture. Both artery wall and plaque components were assumed to be hyperelastic, isotropic, incompressible and homogeneous. Blood… More >
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