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  • Open Access

    ARTICLE

    Computational simulation of postoperative pulmonary flow distribution in Alagille patients with peripheral pulmonary artery stenosis

    Weiguang Yang1, Frank L. Hanley2, Frandics P. Chan3, Alison L. Marsden1,4, Irene E. Vignon-Clementel5, Jeffrey A. Feinstein1,4

    Congenital Heart Disease, Vol.13, No.2, pp. 241-250, 2018, DOI:10.1111/chd.12556

    Abstract Background: Up to 90% of individuals with Alagille syndrome have congenital heart diseases. Peripheral pulmonary artery stenosis (PPS), resulting in right ventricular hypertension and pulmonary flow disparity, is one of the most common abnormalities, yet the hemodynamic effects are illdefined, and optimal patient management and treatment strategies are not well established. The purpose of this pilot study is to use recently refined computational simulation in the setting of multiple surgical strategies, to examine the influence of pulmonary artery reconstruction on hemodynamics in this population.
    Materials and Methods: Based on computed tomography angiography and cardiac catheterization data, preoperative pulmonary artery models… More >

  • Open Access

    ARTICLE

    A composite noninvasive index correlates with liver fibrosis scores in post-Fontan patients: Preliminary findings

    William N. Evans1,2, Ruben J. Acherman1,2, Michael L. Ciccolo1,3, Sergio A. Carrillo1,2, Alvaro Galindo1,2, Abraham Rothman1,2, Gary A. Mayman1,2, Elizabeth A. Adams1,2, Leigh C. Reardon1,4, Brody J. Winn5, Noel S. Yumiaco5, Lesley Shimuizu1, Yoko Inanaga1, Rowena J. Deleon1, Humberto Restrepo1,2

    Congenital Heart Disease, Vol.13, No.1, pp. 38-45, 2018, DOI:10.1111/chd.12558

    Abstract Objective: We hypothesized that clinic-based, hepatic-ultrasound, elastography measurements, either alone or in combination with other noninvasive variables, might correlate with liver-biopsy fibrosis scores in patients post-Fontan.
    Methods: Between March 2012 and February 2017, we identified patients post-Fontan that underwent elective cardiac catheterization and simultaneous transvenous hepatic biopsy. From this group, we selected patients that met inclusion criteria for liver-ultrasound, shear-wave elastography. Utilizing the results of elastography, laboratory testing, and time post-Fontan, we constructed a composite Fontan hepatic index as a sum of elastography measurements in kilopascals, model for end-stage liver disease excluding INR scores, and the square root of the… More >

  • Open Access

    INTRODUCTION

    Proceedings of the International PDA Symposium

    Douglas S. Moodie1, Shyam Sathanandam2, Athar M. Qureshi3

    Congenital Heart Disease, Vol.14, No.1, pp. 5-5, 2019, DOI:10.1111/chd.12761

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    “Frontiers in Fontan failure: A summary of conference proceedings”

    Camden Hebson1,2, Wendy Book1, Robert W. Elder3, Ryan Ford4, Maan Jokhadar1, Kirk Kanter5, Brian Kogon5, Adrienne H. Kovacs6, Rebecca D. Levit1, Michael Lloyd1, Kevin Maher2, Preeti Reshamwala4, Fred Rodriguez III1,2, Rene Romero7, Thor Tejada1, Anne Marie Valente8, Gruschen Veldtman9, Michael McConnell1,2

    Congenital Heart Disease, Vol.12, No.1, pp. 6-16, 2017

    Abstract “Frontiers in Fontan Failure” was the title of a 2015 conference sponsored by Children’s Healthcare of Atlanta and Emory University School of Medicine. In what is hoped to be the first of many such gatherings, speakers and attendees gathered to discuss the problem of long-term clinical deterioration in these patients. Specific focuses included properly defining the problem and then discussing different treatment strategies, both medical and surgical. The health of the liver after Fontan palliation was a particular point of emphasis, as were quality of life and future directions. More >

  • Open Access

    ARTICLE

    Vegetative Compatibility and Virulence Diversity of Verticillium dahliae from Okra (Abelmoschus esculentus) Plantations in Turkey and Evaluation of Okra Landraces for Resistance to V. dahliae

    Fatih M. Tok1, Sibel Dervis2,*, Halit Yetisir3

    Phyton-International Journal of Experimental Botany, Vol.89, No.2, pp. 303-314, 2020, DOI:10.32604/phyton.2020.08801

    Abstract Forty-four V. dahliae isolates were collected from symptomatic vascular tissues of okra plants each from a different field in eight provinces located in the eastern Mediterranean and western Anatolia regions of Turkey during 2006- 2009. Nitrate-nonutilizing (nit) mutants of V. dahliae from okra were used to determine heterokaryosis and genetic relatedness among isolates. All isolates from okra plants were grouped into two vegetative compatibility groups (VCGs) (1 and 2) and three subgroups as 1A (13.6%, 6/44), 2A (20.5%, 9/44) and 2B (65.9%, 29/44) according to international criteria. Pathogenicity tests were performed on a susceptible local okra (A. esculentus) landrace in… More >

  • Open Access

    ARTICLE

    Energy Efficiency in Internet of Things: An Overview

    Wuxiong Zhang1, 2, Weidong Fang1, 2, *, Qianqian Zhao1, 2, Xiaohong Ji3, Guoqing Jia3

    CMC-Computers, Materials & Continua, Vol.63, No.2, pp. 787-811, 2020, DOI:10.32604/cmc.2020.07620

    Abstract Energy efficiency is very important for the Internet of Things (IoT), especially for front-end sensed terminal or node. It not only embodies the node’s life, but also reflects the lifetime of the network. Meanwhile, it is also a key indicator of green communications. Unfortunately, there is no article on systematic analysis and review for energy efficiency evaluation in IoT. In this paper, we systemically analyze the architecture of IoT, and point out its energy distribution, Furthermore, we summarized the energy consumption model in IoT, analyzed the pros and cons of improving energy efficiency, presented a state of the art the… More >

  • Open Access

    ARTICLE

    Safflower (Carthamus Tinctorius L.) a Potential Source of Drugs against Cryptococcal Infections, Malaria and Leishmaniasis

    Aknur Turgumbayeva1,2, Gulbaram Ustenova1, Ubaidilla Datkhayev1, Khairolla Rahimov3, Silvijus Abramavicius4,5, Agile Tunaityte4,*, Kairat Zhakipbekov1,6, Kaldanay Kozhanova1, Saken Tulemissov7, OzikhanUstenova8, Gulmira Datkayeva9, Edgaras Stankevicius1,10

    Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 137-146, 2020, DOI:10.32604/phyton.2020.07665

    Abstract In this research we present that Carthamus Tinctorius L. (gen. Asteraceae, otherwise known as Safflower) (Fig. 1) may contain agents active in Cryptococcal infections, malaria and Leishmaniasis, as treatment options are becoming scarce due to drug resistance development. Phytochemistry and pharmacological activities (antimicrobial, antimalarial, antileishmanial) of C. tinctorius L. were analyzed. The composition of volatile oil of safflower dried flowers was analyzed by gas chromatography-mass spectrophotometry with flame ionization detector (GC-FID) and in vitro sensitivity assays were performed to assess biological activity. 8 known and 3 unknown compounds were detected in the extract (Fig. 1). Then the Safflower ointment was… More >

  • Open Access

    ARTICLE

    Stress Ameliorative Effects of Indole Acetic Acid on Hordeum vulgare L. Seedlings Subjected to Zinc Toxicity

    Monika Sood1, Shanti S. Sharma1, Joginder Singh1, Ram Prasad2,3,*, Dhriti Kapoor1,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 71-86, 2020, DOI:10.32604/phyton.2020.07180

    Abstract The heavy metals present in the environment accumulate in the plants and affect their productivity and yield. By entering the food chain, metals cause several serious health problems in human beings as well as in other organisms. Indole acetic acid (IAA) is known to act as a signaling molecule between symbiotic association of metal accumulating plants and plant growth promoting rhizobacteria (PGPR). Present study demonstrated a protective role of IAA against surplus Zinc (Zn)-induced toxicity to Hordeum vulgare seedlings. Elevated Zn concentrations suppressed the plant growth, caused a reduction in leaf relative water contents (RWC) and elevated free proline and… More >

  • Open Access

    ARTICLE

    Characteristic Tensor for Evaluation of Singular Stress Field Under Mixed-Mode Loadings

    Kei Saito1, 2, *, Tei Hirashima1, Ninshu Ma2, *, Hidekazu Murakawa2

    CMES-Computer Modeling in Engineering & Sciences, Vol.122, No.2, pp. 415-432, 2020, DOI:10.32604/cmes.2020.08847

    Abstract A characteristic tensor is defined using stress tensor averaged in a small circular domain at the crack tip and multiplied by the root of domain radius. It possesses the original stress tensor characteristics and has a simple relationship with conventional fracture-mechanics parameters. Therefore, it can be used to estimate stress intensity factors (SIFs) for cracks of arbitrary shape subjected to multiaxial stress loads. A characteristic tensor can also be used to estimate SIFs for kinked cracks. This study examines the relation between a characteristic tensor and SIFs to demonstrate the correlation between the characteristic tensor and fracture-mechanics parameters. Consequently, a… More >

  • Open Access

    Cardboard-Based Packaging Materials as Renewable Thermal Insulation of Buildings: Thermal and Life-Cycle Performance

    M. Čekon*, K. Struhala, R. Slávik

    Journal of Renewable Materials, Vol.5, Suppl.1, pp. 84-93, 2017, DOI:10.7569/JRM.2017.634135

    Abstract Cardboard-based packaging components represent a material that has significant potential as a renewable source for exploitation in buildings. This study presents the results of thermal and environmental analyses of existing packaging materials compared with standard conventional thermal insulations.
    Experimental measurements were performed to identify the thermal performance of studied cardboard packaging materials. Real-size samples were experimentally tested in laboratory measurements. The thermal resistance and conductivity of all the analyzed samples were measured according to the procedure indicated in the ISO8032 standard. A life-cycle assessment according to ISO 14040 was also performed to evaluate the environmental impacts related to the… More >

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