FRANCESCO PADUANO1,2,*, EMANUELA ALTOMARE2,3, BENEDETTA MARRELLI1, VINCENZO DATTILO4, HAIZAL MOHD HUSSAINI5, PAUL ROY COOPER5, MARCO TATULLO6
BIOCELL, Vol.46, No.8, pp. 1827-1835, 2022, DOI:10.32604/biocell.2022.020462
Abstract Oral Cancer (OC) is one of the most recurrent cancers in the head and neck squamous cancer (SCCHN)
category. Recently, the genome-wide association studies (GWAS) have gained growing interest in the scientific
community. GWAS have identified several pathways involved in the interactions among general risk factors and
genomic variants affecting SCCHN. This systematic overview aims to critically evaluate the latest data reported within
the scientific literature. The aim was to investigate the impact of genetic aspects on SCCHN onset and prognosis,
involving other clinical and systemic co-factors. PubMed, Google Scholar, and Cancer Genetics Web databases have
been systematically investigated for… More >
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