ABDELKADER HASSANI1,2,3, SITI ASLINA HUSSAIN2, MOTHANNA SADIQ AL-QUBAISI4, MOHAMED LAKHDER BELFAR3, HAKIM BELKHALFA5, HAMID HAMMAD ENEZEI6, HAMID ZENTOU2, WISAM NABEEL IBRAHIM7,8,*, ABD ALMONEM DOOLAANEA1,*
BIOCELL, Vol.46, No.3, pp. 677-687, 2022, DOI:10.32604/biocell.2022.016848
Abstract The main purpose of the study was to enhance the stability and therapeutic effects of Curcumin (Cur) through nanoformulation with gum Arabic (GA) as a coating agent through an efficient synthetic approach. The antioxidant properties of the developed nanoparticles (Cur/GANPs) were assessed through several in vitro assays, such as β-carotene bleaching activity, DPPH, and nitric oxide scavenging activities in addition to evaluating its inhibitory activity on angiotensin-converting enzyme (ACE). The cytotoxicity of Cur/GANPs was evaluated in vitro using different types of human cancer cells including breast cancer (MCF7, MDA-MB231), liver cancer (HepG2), and colon cancer (HT29) cells. The prepared particles… More >
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